Acetaminophen And Codeine Phosphate
Generic Name: acetaminophen and codeine phosphate
Brand Names:
Acetaminophen And Codeine Phosphate
Acetaminophen and codeine phosphate is a combination of acetaminophen, a non-opiate, non-salicylate analgesic and antipyretic, and codeine phosphate, a narcotic analgesic and antitussive. It is a Schedule III controlled substance used for pain management.
Overview
Acetaminophen and codeine phosphate is a combination of acetaminophen, a non-opiate, non-salicylate analgesic and antipyretic, and codeine phosphate, a narcotic analgesic and antitussive. It is a Schedule III controlled substance used for pain management.
Uses
Indicated for the management of mild to moderate pain where opioid treatment is appropriate and alternative treatments are inadequate.
Dosage
Dosage should be adjusted according to the severity of pain and the response of the patient. Consult prescribing information for specific dosing guidelines based on codeine and acetaminophen content.
Side Effects
Serious, life-threatening, or fatal respiratory depression has been reported with the use of opioids, even when used as recommended. Other risks include addiction, abuse, and misuse.
Interactions
CYP2D6 and CYP3A4 inhibitors and inducers may affect codeine metabolism. Use with benzodiazepines or other CNS depressants may result in profound sedation, respiratory depression, coma, and death. Interactions with serotonergic drugs, MAOIs, muscle relaxants, and anticholinergic agents.
Warnings
Addiction, Abuse, and Misuse: Risk of opioid addiction, abuse, and misuse which can lead to overdose and death. Respiratory Depression: Serious, life-threatening respiratory depression may occur. Neonatal Opioid Withdrawal Syndrome: Prolonged use during pregnancy can cause withdrawal in the newborn. Contraindicated in children under 12 years of age and post-operative management in children under 18 following tonsillectomy or adenoidectomy.
Pregnancy
Neonatal opioid withdrawal syndrome may occur with prolonged use during pregnancy. Symptoms include irritability, hyperactivity, abnormal sleep pattern, high pitched cry, tremor, vomiting, and diarrhea.
Frequently Asked Questions
What is Acetaminophen And Codeine Phosphate used for?▼
Indicated for the management of mild to moderate pain where opioid treatment is appropriate and alternative treatments are inadequate.
What are the side effects of Acetaminophen And Codeine Phosphate?▼
Serious, life-threatening, or fatal respiratory depression has been reported with the use of opioids, even when used as recommended. Other risks include addiction, abuse, and misuse.
Can I take Acetaminophen And Codeine Phosphate during pregnancy?▼
Neonatal opioid withdrawal syndrome may occur with prolonged use during pregnancy. Symptoms include irritability, hyperactivity, abnormal sleep pattern, high pitched cry, tremor, vomiting, and diarrhea.
What are the important warnings for Acetaminophen And Codeine Phosphate?▼
Addiction, Abuse, and Misuse: Risk of opioid addiction, abuse, and misuse which can lead to overdose and death. Respiratory Depression: Serious, life-threatening respiratory depression may occur. Neonatal Opioid Withdrawal Syndrome: Prolonged use during pregnancy can cause withdrawal in the newborn. Contraindicated in children under 12 years of age and post-operative management in children under 18 following tonsillectomy or adenoidectomy.
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Medical Disclaimer
This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.