Amlodipine And Benazepril Hydrochloride

Generic Name: amlodipine and benazepril hydrochloride

Over-the-Counter (OTC)

Brand Names:

Amlodipine and benazepril hydrochloride capsules are a combination of the calcium channel blocker amlodipine besylate and the ACE inhibitor benazepril hydrochloride for oral administration.

Overview

Amlodipine and benazepril hydrochloride capsules are a combination of the calcium channel blocker amlodipine besylate and the ACE inhibitor benazepril hydrochloride for oral administration.

Uses

Indicated for the treatment of hypertension in patients not adequately controlled on monotherapy with either agent.

Dosage

Usual starting dose is 2.5 mg/10 mg taken orally once daily. May be titrated up to amlodipine 10 mg and benazepril 40 mg once daily based on patient response.

Side Effects

Most common reasons for discontinuation were cough (3.3%) and edema (2.1%). Other side effects include headache, dizziness, asthenia, flushing, dry mouth, nausea, and muscle cramps.

Interactions

Interactions with potassium supplements, lithium, NSAIDs, simvastatin (limit to 20 mg daily), mTOR inhibitors, and neprilysin inhibitors.

Warnings

BOXED WARNING: Fetal toxicity. When pregnancy is detected, discontinue as soon as possible. Risks include anaphylactoid reactions, angioedema, hypotension, renal impairment, and hyperkalemia. Do not coadminister aliskiren in patients with diabetes.

Pregnancy

Can cause fetal harm when administered to a pregnant woman, with risks including oligohydramnios and neonatal complications. Discontinue when pregnancy is detected.

Storage

Store at 20 to 25 degrees C (68 to 77 degrees F); excursions permitted to 15 to 30 degrees C (59 to 86 degrees F).

Frequently Asked Questions

What is Amlodipine And Benazepril Hydrochloride used for?▼

Indicated for the treatment of hypertension in patients not adequately controlled on monotherapy with either agent.

What are the side effects of Amlodipine And Benazepril Hydrochloride?▼

Most common reasons for discontinuation were cough (3.3%) and edema (2.1%). Other side effects include headache, dizziness, asthenia, flushing, dry mouth, nausea, and muscle cramps.

Can I take Amlodipine And Benazepril Hydrochloride during pregnancy?▼

Can cause fetal harm when administered to a pregnant woman, with risks including oligohydramnios and neonatal complications. Discontinue when pregnancy is detected.

What are the important warnings for Amlodipine And Benazepril Hydrochloride?▼

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Medical Disclaimer

This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.