Amlodipine Besylate And Benazepril Hydrochloride

Generic Name: amlodipine besylate and benazepril hydrochloride

Over-the-Counter (OTC)

Brand Names:

Amlodipine besylate and benazepril hydrochloride capsules are a combination antihypertensive available in six strengths (2.5/10, 5/10, 5/20, 5/40, 10/20, 10/40 mg) for oral administration.

Overview

Amlodipine besylate and benazepril hydrochloride capsules are a combination antihypertensive available in six strengths (2.5/10, 5/10, 5/20, 5/40, 10/20, 10/40 mg) for oral administration.

Uses

Indicated for the treatment of hypertension in patients not adequately controlled on monotherapy with either agent.

Dosage

Initial dose is one capsule of 2.5 mg/10 mg once daily. Maximum dose is 10 mg/40 mg once daily. Antihypertensive effect largely attained within 2 weeks.

Side Effects

Most common reasons for discontinuation were cough (3.3%) and edema (2.1%). Other side effects include headache (2.2%), dizziness (1.3%), asthenia, flushing, dry mouth, nausea, and muscle cramps.

Interactions

Interactions with potassium supplements, lithium, NSAIDs, simvastatin (limit to 20 mg daily), mTOR inhibitors, and neprilysin inhibitors.

Warnings

BOXED WARNING: Fetal toxicity. Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus. Risks include angioedema, hypotension, hyperkalemia. Contraindicated with neprilysin inhibitors and in patients with angioedema history.

Pregnancy

Can cause fetal harm when administered to a pregnant woman. When pregnancy is detected, discontinue as soon as possible.

Storage

Store at 25 degrees C (77 degrees F); excursions permitted to 15 to 30 degrees C (59 to 86 degrees F). Protect from moisture.

Frequently Asked Questions

What is Amlodipine Besylate And Benazepril Hydrochloride used for?▼

Indicated for the treatment of hypertension in patients not adequately controlled on monotherapy with either agent.

What are the side effects of Amlodipine Besylate And Benazepril Hydrochloride?▼

Most common reasons for discontinuation were cough (3.3%) and edema (2.1%). Other side effects include headache (2.2%), dizziness (1.3%), asthenia, flushing, dry mouth, nausea, and muscle cramps.

Can I take Amlodipine Besylate And Benazepril Hydrochloride during pregnancy?▼

Can cause fetal harm when administered to a pregnant woman. When pregnancy is detected, discontinue as soon as possible.

What are the important warnings for Amlodipine Besylate And Benazepril Hydrochloride?▼

Related Medications

Borago Officinalis Flower

borago officinalis flower

Dosage form: LIQUID. Active ingredients: BORAGO OFFICINALIS FLOWER (1 [hp_X]/mL). Category: DRUG FOR FURTHER PROCESSING.

Acamprosate Calcium

acamprosate calcium

11 DESCRIPTION Acamprosate calcium delayed-release tablets are supplied as an enteric-coated tablet for oral administration. Acamprosate calcium, USP is a synthetic compound with a chemical structure similar to that of the endogenous amino acid homotaurine, which is a structural analogue of the amino acid neurotransmitter γ-aminobutyric acid and the amino acid neuromodulator taurine. Its chemical name is calcium bis [3-(acetylamino) propane-1-sulfonate].

Fexinidazole

fexinidazole

Nitroimidazole Antimicrobial [EPC]

11 DESCRIPTION Fexinidazole Tablets contain fexinidazole, a nitroimidazole antimicrobial drug for oral use. The chemical name of fexinidazole is 1-methyl-2-{[4-(methylthio)phenoxy]methyl}-5-nitro-1H-imidazole. Its molecular formula is C 12 H 13 N 3 O 3 S and the molecular weight is 279.3 g/mol. The structural formula is: Fexinidazole is a yellow powder.

Medical Disclaimer

This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.