Articaine Hydrochloride And Epinephrine
Generic Name: articaine hydrochloride and epinephrine
Brand Names:
Articaine
Articaine HCl and Epinephrine is a sterile, aqueous solution containing articaine HCl 4% (40 mg/mL) and epinephrine bitartrate for intraoral submucosal infiltration use as a dental anesthetic.
Overview
Articaine HCl and Epinephrine is a sterile, aqueous solution containing articaine HCl 4% (40 mg/mL) and epinephrine bitartrate for intraoral submucosal infiltration use as a dental anesthetic.
Uses
Indicated for local, infiltrative, or conductive anesthesia in both simple and complex dental procedures in adults and pediatric patients 4 years of age or older.
Dosage
For infiltration: 0.5-2.5 mL (20-100 mg); nerve block: 0.5-3.4 mL (20-136 mg); oral surgery: 1.0-5.1 mL (40-204 mg). Maximum recommended dosage: 7 mg/kg of articaine HCl for healthy adults and pediatric patients 4-16 years.
Side Effects
Most common: headache and pain. Others include face edema, infection, gingivitis, paresthesia, swelling, trismus, nausea. Postmarketing reports of persistent paresthesias of the lips, tongue, and oral tissues.
Interactions
Concurrent use with MAO inhibitors, nonselective beta-blockers, or tricyclic antidepressants may produce severe, prolonged hypertension. Concurrent exposure to oxidizing agents increases methemoglobinemia risk.
Warnings
Accidental intravascular injection may cause convulsions followed by coma and respiratory arrest. Risk of systemic toxicity, vasoconstrictor toxicity, methemoglobinemia. Contraindicated in patients hypersensitive to products containing sulfites.
Pregnancy
Pregnancy Category C. Should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Storage
Store at controlled room temperature 25 degrees C (77 degrees F) with brief excursions permitted between 15 and 30 degrees C. Protect from light. Do not freeze.
Frequently Asked Questions
What is Articaine Hydrochloride And Epinephrine used for?▼
Indicated for local, infiltrative, or conductive anesthesia in both simple and complex dental procedures in adults and pediatric patients 4 years of age or older.
What are the side effects of Articaine Hydrochloride And Epinephrine?▼
Most common: headache and pain. Others include face edema, infection, gingivitis, paresthesia, swelling, trismus, nausea. Postmarketing reports of persistent paresthesias of the lips, tongue, and oral tissues.
Can I take Articaine Hydrochloride And Epinephrine during pregnancy?▼
Pregnancy Category C. Should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
What are the important warnings for Articaine Hydrochloride And Epinephrine?▼
Accidental intravascular injection may cause convulsions followed by coma and respiratory arrest. Risk of systemic toxicity, vasoconstrictor toxicity, methemoglobinemia. Contraindicated in patients hypersensitive to products containing sulfites.
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Medical Disclaimer
This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.