Atropine Sulfate

Generic Name: atropine sulfate

Over-the-Counter (OTC)

Brand Names:

Atropine Sulfate

Atropine Sulfate Injection is a sterile, nonpyrogenic isotonic solution of atropine sulfate monohydrate in water for injection. Used as an antimuscarinic agent.

Overview

Atropine Sulfate Injection is a sterile, nonpyrogenic isotonic solution of atropine sulfate monohydrate in water for injection. Used as an antimuscarinic agent.

Uses

Indicated for temporary blockade of severe or life-threatening muscarinic effects, as an antisialagogue, an antivagal agent, an antidote for organophosphorus or muscarinic mushroom poisoning, and to treat bradyasystolic cardiac arrest.

Dosage

For intravenous administration. Titrate based on heart rate, PR interval, blood pressure and symptoms. Adult dosage varies by use: 0.5-1 mg for antisialagogue; 2-3 mg repeated every 20-30 minutes for poisoning; 1 mg repeated every 3-5 minutes for cardiac arrest.

Side Effects

Most adverse reactions are directly related to antimuscarinic action. Dryness of the mouth, blurred vision, photophobia and tachycardia commonly occur with chronic administration.

Interactions

Decreased the rate of mexiletine absorption without altering the relative oral bioavailability.

Warnings

Risks include tachycardia, acute glaucoma, pyloric obstruction, complete urinary retention, and viscid bronchial plugs formation. No absolute contraindications.

Pregnancy

Animal reproduction studies have not been conducted with atropine. It is not known whether atropine can cause fetal harm when given to a pregnant woman.

Storage

1 mL in a carton, 10 in a package.

Frequently Asked Questions

What is Atropine Sulfate used for?

Indicated for temporary blockade of severe or life-threatening muscarinic effects, as an antisialagogue, an antivagal agent, an antidote for organophosphorus or muscarinic mushroom poisoning, and to treat bradyasystolic cardiac arrest.

What are the side effects of Atropine Sulfate?

Most adverse reactions are directly related to antimuscarinic action. Dryness of the mouth, blurred vision, photophobia and tachycardia commonly occur with chronic administration.

Can I take Atropine Sulfate during pregnancy?

Animal reproduction studies have not been conducted with atropine. It is not known whether atropine can cause fetal harm when given to a pregnant woman.

What are the important warnings for Atropine Sulfate?

Risks include tachycardia, acute glaucoma, pyloric obstruction, complete urinary retention, and viscid bronchial plugs formation. No absolute contraindications.

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Medical Disclaimer

This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.