Benazepril Hydrochloride
Generic Name: benazepril hydrochloride
Brand Names:
Benazepril Hydrochloride
Benazepril hydrochloride is an ACE inhibitor for oral administration used in the treatment of hypertension to lower blood pressure and reduce cardiovascular risk.
Overview
Benazepril hydrochloride is an ACE inhibitor for oral administration used in the treatment of hypertension to lower blood pressure and reduce cardiovascular risk.
Uses
Indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions.
Dosage
Adults: Initial 10 mg once daily (5 mg if on diuretic); titrate up to 40 mg daily. Pediatric (age 6 and older): 0.2 mg/kg once daily, maximum 0.6 mg/kg daily. Renal impairment (GFR below 30): 5 mg once daily.
Side Effects
Most common adverse reactions compared to placebo: headache (6% vs. 4%), dizziness (4% vs. 2%), somnolence (2% vs. 0%).
Interactions
Interactions with diuretics, antidiabetics, NSAIDs, dual RAS blockade agents, lithium, mTOR inhibitors, and gold compounds. Use caution with concurrent medications.
Warnings
WARNING: FETAL TOXICITY - When pregnancy is detected, discontinue benazepril hydrochloride tablets as soon as possible. Risk of angioedema, impaired renal function, hypotension, hyperkalemia, and hepatic failure. Contraindicated in patients with hypersensitivity, angioedema history, or concurrent neprilysin inhibitors.
Pregnancy
When pregnancy is detected, discontinue as soon as possible. Drugs that act on the renin-angiotensin system can cause injury and death to the developing fetus.
Storage
Store at 20-25C (68-77F). Protect from moisture.
Frequently Asked Questions
What is Benazepril Hydrochloride used for?▼
Indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions.
What are the side effects of Benazepril Hydrochloride?▼
Most common adverse reactions compared to placebo: headache (6% vs. 4%), dizziness (4% vs. 2%), somnolence (2% vs. 0%).
Can I take Benazepril Hydrochloride during pregnancy?▼
When pregnancy is detected, discontinue as soon as possible. Drugs that act on the renin-angiotensin system can cause injury and death to the developing fetus.
What are the important warnings for Benazepril Hydrochloride?▼
WARNING: FETAL TOXICITY - When pregnancy is detected, discontinue benazepril hydrochloride tablets as soon as possible. Risk of angioedema, impaired renal function, hypotension, hyperkalemia, and hepatic failure. Contraindicated in patients with hypersensitivity, angioedema history, or concurrent neprilysin inhibitors.
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Medical Disclaimer
This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.