Brimonidine Tartrate And Timolol Maleate

Generic Name: brimonidine tartrate and timolol maleate

Over-the-Counter (OTC)

Brand Names:

Brimonidine Tartrate/timolol Maleate Ophthalmic Solution

Brimonidine tartrate and timolol maleate ophthalmic solution combines an alpha-2 adrenergic receptor agonist with a non-selective beta-adrenergic receptor inhibitor, indicated for the reduction of elevated intraocular pressure in patients with glaucoma or ocular hypertension.

Overview

Brimonidine tartrate and timolol maleate ophthalmic solution combines an alpha-2 adrenergic receptor agonist with a non-selective beta-adrenergic receptor inhibitor, indicated for the reduction of elevated intraocular pressure in patients with glaucoma or ocular hypertension.

Uses

Indicated for the reduction of elevated intraocular pressure (IOP) in patients with glaucoma or ocular hypertension who require adjunctive or replacement therapy due to inadequately controlled IOP.

Dosage

One drop in the affected eye(s) twice daily approximately 12 hours apart. Different topical ophthalmic products should be administered at least 5 minutes apart.

Side Effects

Most common (5-15%): allergic conjunctivitis, conjunctival folliculosis, conjunctival hyperemia, eye pruritus, ocular burning, and stinging. Serious reactions possible include bronchospasm, cardiac failure, and systemic effects typical of beta-blockers.

Interactions

Interactions include antihypertensives and cardiac glycosides, systemic beta-blockers, calcium antagonists, catecholamine-depleting drugs, CNS depressants, and MAO inhibitors.

Warnings

Contains timolol maleate which can be absorbed systemically. Contraindicated in patients with bronchial asthma, severe COPD, sinus bradycardia, atrioventricular block, overt cardiac failure, cardiogenic shock, age under 2 years, and hypersensitivity to any component.

Storage

Store at 20 to 25 degrees C (68 to 77 degrees F). Protect from light.

Frequently Asked Questions

What is Brimonidine Tartrate And Timolol Maleate used for?

Indicated for the reduction of elevated intraocular pressure (IOP) in patients with glaucoma or ocular hypertension who require adjunctive or replacement therapy due to inadequately controlled IOP.

What are the side effects of Brimonidine Tartrate And Timolol Maleate?

Most common (5-15%): allergic conjunctivitis, conjunctival folliculosis, conjunctival hyperemia, eye pruritus, ocular burning, and stinging. Serious reactions possible include bronchospasm, cardiac failure, and systemic effects typical of beta-blockers.

What are the important warnings for Brimonidine Tartrate And Timolol Maleate?

Contains timolol maleate which can be absorbed systemically. Contraindicated in patients with bronchial asthma, severe COPD, sinus bradycardia, atrioventricular block, overt cardiac failure, cardiogenic shock, age under 2 years, and hypersensitivity to any component.

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Medical Disclaimer

This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.