Cholestyramine

Generic Name: cholestyramine

Bile Acid Sequestrant [EPC]Over-the-Counter (OTC)

Brand Names:

Cholestyramine

Cholestyramine is a cholesterol-lowering anion exchange resin indicated as adjunctive therapy to diet for the reduction of elevated serum cholesterol in patients with primary hypercholesterolemia and for relief of pruritus associated with partial biliary obstruction.

Overview

Cholestyramine is a cholesterol-lowering anion exchange resin indicated as adjunctive therapy to diet for the reduction of elevated serum cholesterol in patients with primary hypercholesterolemia and for relief of pruritus associated with partial biliary obstruction.

Uses

Indicated as adjunctive therapy to diet for the reduction of elevated serum cholesterol in patients with primary hypercholesterolemia and for relief of pruritus associated with partial biliary obstruction.

Dosage

Starting dose is 1 pouch or 1 level scoopful (9 grams) once or twice a day. Maintenance dosing ranges from 2 to 4 pouches daily (8 to 16 grams). Maximum recommended daily dose is 6 pouches or scoopfuls.

Side Effects

The most common adverse reaction is constipation. Additional effects include abdominal discomfort, flatulence, nausea, vomiting, and vitamin deficiencies including Vitamins A, D, and K.

Interactions

Cholestyramine may delay or reduce the absorption of concomitant oral medication including warfarin, thiazide diuretics, and digitalis. Patients should take other drugs at least 1 hour before or 4-6 hours after this medication.

Warnings

Contraindicated in patients with complete biliary obstruction and hypersensitivity to any components.

Pregnancy

There are no adequate and well controlled studies in pregnant women. Potential benefits must be weighed against possible hazards to mother and child.

Frequently Asked Questions

What is Cholestyramine used for?

Indicated as adjunctive therapy to diet for the reduction of elevated serum cholesterol in patients with primary hypercholesterolemia and for relief of pruritus associated with partial biliary obstruction.

What are the side effects of Cholestyramine?

The most common adverse reaction is constipation. Additional effects include abdominal discomfort, flatulence, nausea, vomiting, and vitamin deficiencies including Vitamins A, D, and K.

Can I take Cholestyramine during pregnancy?

There are no adequate and well controlled studies in pregnant women. Potential benefits must be weighed against possible hazards to mother and child.

What are the important warnings for Cholestyramine?

Contraindicated in patients with complete biliary obstruction and hypersensitivity to any components.

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Medical Disclaimer

This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.