Ciprofloxacin
Generic Name: ciprofloxacin
Brand Names:
Ciprofloxacin
Ciprofloxacin is a fluoroquinolone antibacterial agent indicated for treating various infections caused by susceptible bacteria in adults and select pediatric patients.
Overview
Ciprofloxacin is a fluoroquinolone antibacterial agent indicated for treating various infections caused by susceptible bacteria in adults and select pediatric patients.
Uses
Indicated in adults for skin and skin structure infections, bone and joint infections, complicated intra-abdominal infections, infectious diarrhea, typhoid fever, gonorrhea, inhalational anthrax post-exposure, plague, chronic bacterial prostatitis, lower respiratory tract infections, urinary tract infections, and acute sinusitis.
Dosage
Adult dosing ranges from 250 to 750 mg every 12 hours depending on infection type, with durations from single-dose to 60 days. Pediatric dosing: 10-20 mg/kg every 12 hours for UTI (maximum 750 mg), or 15 mg/kg every 8-12 hours for plague/anthrax. Take at least 2 hours before or 6 hours after multivalent cation-containing products.
Side Effects
Most common adverse reactions: nausea (2.5%), diarrhea (1.6%), liver function abnormalities (1.3%), vomiting (1%), and rash (1%). Serious effects include tendinitis, tendon rupture, peripheral neuropathy, and CNS effects.
Interactions
Contraindicated with tizanidine. Avoid theophylline and QT-prolonging drugs. Use caution with antidiabetic agents, warfarin, methotrexate, phenytoin, and cyclosporine. Multivalent cations reduce absorption.
Warnings
Fluoroquinolones are associated with disabling and potentially irreversible serious adverse reactions including tendinitis, tendon rupture, peripheral neuropathy, and CNS effects. Reserve for patients with no alternative treatment options for certain indications. Additional warnings for hepatotoxicity, QT prolongation, myasthenia gravis exacerbation, and aortic aneurysm risk. Contraindicated with tizanidine.
Frequently Asked Questions
What is Ciprofloxacin used for?▼
Indicated in adults for skin and skin structure infections, bone and joint infections, complicated intra-abdominal infections, infectious diarrhea, typhoid fever, gonorrhea, inhalational anthrax post-exposure, plague, chronic bacterial prostatitis, lower respiratory tract infections, urinary tract infections, and acute sinusitis.
What are the side effects of Ciprofloxacin?▼
Most common adverse reactions: nausea (2.5%), diarrhea (1.6%), liver function abnormalities (1.3%), vomiting (1%), and rash (1%). Serious effects include tendinitis, tendon rupture, peripheral neuropathy, and CNS effects.
What are the important warnings for Ciprofloxacin?▼
Fluoroquinolones are associated with disabling and potentially irreversible serious adverse reactions including tendinitis, tendon rupture, peripheral neuropathy, and CNS effects. Reserve for patients with no alternative treatment options for certain indications. Additional warnings for hepatotoxicity, QT prolongation, myasthenia gravis exacerbation, and aortic aneurysm risk. Contraindicated with tizanidine.
Related Medications
Primidone
primidone
Anti-epileptic Agent [EPC]
DESCRIPTION Primidone, USP is a white, crystalline, highly stable substance, M.P. 279-284° C. It is poorly soluble in water (60 mg per 100 mL at 37° C) and in most organic solvents. It possesses no acidic properties, in contrast to its barbiturate analog. Chemical name: 5-ethyldihydro-5-phenyl-4,6 (1H, 5H)-pyrimidinedione.
Cerebrum Suis
cerebrum suis
PURPOSE: Cerebrum Suis - restlessness** **Claims based on traditional homeopathic practice, not accepted medial evidence. Not FDA evaluated.
Gallium Phosphoricum
gallium phosphoricum
Medical Disclaimer
This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.