Clobetasol Propionate
Generic Name: clobetasol propionate
Brand Names:
Clobetasol Propionate
Clobetasol propionate ointment USP contains the active compound clobetasol propionate, a synthetic corticosteroid, for topical dermatologic use at 0.5 mg/g concentration in a base of propylene glycol, sorbitan sesquioleate, and white petrolatum.
Overview
Clobetasol propionate ointment USP contains the active compound clobetasol propionate, a synthetic corticosteroid, for topical dermatologic use at 0.5 mg/g concentration in a base of propylene glycol, sorbitan sesquioleate, and white petrolatum.
Uses
Super-high potency corticosteroid formulations indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Treatment should not exceed 2 consecutive weeks with maximum dosage of 50 g/week. Not recommended for pediatric patients under 12 years of age.
Dosage
Apply a thin layer of clobetasol propionate ointment USP to the affected skin areas twice daily and rub in gently and completely. Limited to 2 consecutive weeks maximum. Should not be used with occlusive dressings.
Side Effects
Most frequent adverse events include burning sensation, irritation, and itching in 0.5% of treated patients. Less frequent reactions include stinging, cracking, erythema, folliculitis, skin atrophy, and telangiectasia.
Warnings
Contraindicated in those patients with a history of hypersensitivity to any of the components of the preparations.
Pregnancy
Teratogenic effects documented in animal studies. Should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Storage
Available in 15g, 30g, 45g, and 60g tubes. Store at 20-25 degrees C; do not refrigerate.
Frequently Asked Questions
What is Clobetasol Propionate used for?▼
Super-high potency corticosteroid formulations indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Treatment should not exceed 2 consecutive weeks with maximum dosage of 50 g/week. Not recommended for pediatric patients under 12 years of age.
What are the side effects of Clobetasol Propionate?▼
Most frequent adverse events include burning sensation, irritation, and itching in 0.5% of treated patients. Less frequent reactions include stinging, cracking, erythema, folliculitis, skin atrophy, and telangiectasia.
Can I take Clobetasol Propionate during pregnancy?▼
Teratogenic effects documented in animal studies. Should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
What are the important warnings for Clobetasol Propionate?▼
Contraindicated in those patients with a history of hypersensitivity to any of the components of the preparations.
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Medical Disclaimer
This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.