Cyproheptadine Hydrochloride
Generic Name: cyproheptadine hydrochloride
Brand Names:
Cyproheptadine Hydrochloride
White to slightly yellowish crystalline solid containing 4 mg cyproheptadine HCl per tablet with inactive ingredients including lactose monohydrate, microcrystalline cellulose, and magnesium stearate.
Overview
White to slightly yellowish crystalline solid containing 4 mg cyproheptadine HCl per tablet with inactive ingredients including lactose monohydrate, microcrystalline cellulose, and magnesium stearate.
Uses
Treats perennial and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, mild allergic skin manifestations (urticaria/angioedema), blood and plasma allergic reactions, cold urticaria, dermatographism, and serves as adjunctive therapy for anaphylactic reactions.
Dosage
Pediatric (2-6 years): 2 mg two to three times daily, max 12 mg/day. Pediatric (7-14 years): 4 mg two to three times daily, max 16 mg/day. Adults: 4-20 mg daily typically; range up to 32 mg daily possible. Start 4 mg three times daily.
Side Effects
Lists CNS effects (sedation, dizziness, confusion), integumentary reactions (rash, urticaria), cardiovascular effects (hypotension, tachycardia), hematologic disorders, digestive symptoms, and respiratory symptoms.
Interactions
MAO inhibitors intensify anticholinergic effects. Additive effects with alcohol and CNS depressants.
Warnings
Pediatric overdosage risk. CNS depressant interactions. Caution with mental alertness activities and driving. Contraindicated in newborns/prematures, nursing mothers, MAO inhibitor use, angle-closure glaucoma, stenosing peptic ulcer, prostatic hypertrophy, and bladder obstruction.
Pregnancy
Category B. Animal studies showed no fetal harm at therapeutic doses. Human studies showed no increased abnormality risk across trimesters.
Storage
Store at 20-25 degrees C (68-77 degrees F). Dispense in well-closed USP container with child-resistant closure.
Frequently Asked Questions
What is Cyproheptadine Hydrochloride used for?▼
Treats perennial and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, mild allergic skin manifestations (urticaria/angioedema), blood and plasma allergic reactions, cold urticaria, dermatographism, and serves as adjunctive therapy for anaphylactic reactions.
What are the side effects of Cyproheptadine Hydrochloride?▼
Lists CNS effects (sedation, dizziness, confusion), integumentary reactions (rash, urticaria), cardiovascular effects (hypotension, tachycardia), hematologic disorders, digestive symptoms, and respiratory symptoms.
Can I take Cyproheptadine Hydrochloride during pregnancy?▼
Category B. Animal studies showed no fetal harm at therapeutic doses. Human studies showed no increased abnormality risk across trimesters.
What are the important warnings for Cyproheptadine Hydrochloride?▼
Pediatric overdosage risk. CNS depressant interactions. Caution with mental alertness activities and driving. Contraindicated in newborns/prematures, nursing mothers, MAO inhibitor use, angle-closure glaucoma, stenosing peptic ulcer, prostatic hypertrophy, and bladder obstruction.
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Medical Disclaimer
This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.