Dextroamphetamine Sulfate
Generic Name: dextroamphetamine sulfate
Brand Names:
Dextroamphetamine Sulfate Extended-release
Dextroamphetamine sulfate extended-release capsule is the dextro isomer of the compound d,l-amphetamine sulfate, a sympathomimetic amine of the amphetamine group. Each capsule releases an initial dose promptly, with remaining medication released gradually.
Overview
Dextroamphetamine sulfate extended-release capsule is the dextro isomer of the compound d,l-amphetamine sulfate, a sympathomimetic amine of the amphetamine group. Each capsule releases an initial dose promptly, with remaining medication released gradually.
Uses
Indicated for Narcolepsy and Attention Deficit Disorder with Hyperactivity as part of comprehensive treatment programs for patients ages 6-16. Not recommended for children under 6 years.
Dosage
Narcolepsy: 5-60 mg daily in divided doses. Ages 6-12: start 5 mg daily, increase by 5 mg weekly. Ages 12+: start 10 mg daily, increase by 10 mg weekly. ADHD: Start 5 mg once/twice daily for ages 6+; increase by 5 mg weekly. Rarely exceed 40 mg daily.
Side Effects
Common: fast heartbeat, decreased appetite, tremors, headache, insomnia, dizziness, stomach upset, weight loss, dry mouth. Serious: psychotic episodes, cardiomyopathy, palpitations, tachycardia, hypertension, rhabdomyolysis, urticaria.
Interactions
Key interactions: acidifying/alkalinizing agents, tricyclic antidepressants, CYP2D6 inhibitors, serotonergic drugs, MAO inhibitors, proton pump inhibitors, adrenergic blockers, antihypertensives, lithium carbonate.
Warnings
WARNING: ABUSE, MISUSE, AND ADDICTION - High abuse potential leading to substance use disorder. Sudden cardiac death in patients with structural cardiac abnormalities; increased blood pressure and heart rate; psychiatric adverse reactions; growth suppression; seizure threshold lowering; peripheral vasculopathy; serotonin syndrome risk. Contraindicated with known hypersensitivity and MAOIs.
Pregnancy
Animal studies showed embryotoxic and teratogenic effects at high doses. Limited human data. Use only if the potential benefit justifies the potential risk to the fetus.
Storage
Store at controlled room temperature between 20 to 25 degrees C (68 to 77 degrees F). Keep in tight, light-resistant container.
Frequently Asked Questions
What is Dextroamphetamine Sulfate used for?▼
Indicated for Narcolepsy and Attention Deficit Disorder with Hyperactivity as part of comprehensive treatment programs for patients ages 6-16. Not recommended for children under 6 years.
What are the side effects of Dextroamphetamine Sulfate?▼
Common: fast heartbeat, decreased appetite, tremors, headache, insomnia, dizziness, stomach upset, weight loss, dry mouth. Serious: psychotic episodes, cardiomyopathy, palpitations, tachycardia, hypertension, rhabdomyolysis, urticaria.
Can I take Dextroamphetamine Sulfate during pregnancy?▼
Animal studies showed embryotoxic and teratogenic effects at high doses. Limited human data. Use only if the potential benefit justifies the potential risk to the fetus.
What are the important warnings for Dextroamphetamine Sulfate?▼
WARNING: ABUSE, MISUSE, AND ADDICTION - High abuse potential leading to substance use disorder. Sudden cardiac death in patients with structural cardiac abnormalities; increased blood pressure and heart rate; psychiatric adverse reactions; growth suppression; seizure threshold lowering; peripheral vasculopathy; serotonin syndrome risk. Contraindicated with known hypersensitivity and MAOIs.
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Medical Disclaimer
This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.