Dextrose Monohydrate
Generic Name: dextrose monohydrate
Brand Names:
Dextrose
Sterile, nonpyrogenic hypertonic solution containing 0.5 grams dextrose per mL in water for injection.
Overview
Sterile, nonpyrogenic hypertonic solution containing 0.5 grams dextrose per mL in water for injection.
Uses
Treatment of insulin-induced hypoglycemia in adults and pediatric patients aged 2 years and older.
Dosage
Adults and pediatrics 12+: 10-25 grams (20-50 mL) via central or large peripheral vein. Pediatrics 2-11: central vein only. Maximum infusion rate 0.5 g/kg body weight/hour.
Side Effects
Hyperglycemia, hypersensitivity reactions, phlebitis, thrombosis, hyponatremia, electrolyte imbalance, infection, anaphylaxis, and angioedema.
Interactions
Monitor blood glucose and electrolytes with concomitant drugs affecting glycemic control. Avoid concurrent use with agents causing hyponatremia.
Warnings
Risk of hyperglycemia and hyperosmolar state, phlebitis from hypertonic solution, hyponatremia, electrolyte imbalance, aluminum toxicity in renal impairment, and hypersensitivity reactions. Contraindicated in intracranial/intraspinal hemorrhage, severe dehydration, alcohol withdrawal, and dextrose hypersensitivity.
Pregnancy
Appropriate administration not expected to cause birth defects, but maternal hyperglycemia at delivery associated with neonatal hypoglycemia risk.
Storage
Store 20-25 degrees C, protect from freezing and excessive heat.
Frequently Asked Questions
What is Dextrose Monohydrate used for?▼
Treatment of insulin-induced hypoglycemia in adults and pediatric patients aged 2 years and older.
What are the side effects of Dextrose Monohydrate?▼
Hyperglycemia, hypersensitivity reactions, phlebitis, thrombosis, hyponatremia, electrolyte imbalance, infection, anaphylaxis, and angioedema.
Can I take Dextrose Monohydrate during pregnancy?▼
Appropriate administration not expected to cause birth defects, but maternal hyperglycemia at delivery associated with neonatal hypoglycemia risk.
What are the important warnings for Dextrose Monohydrate?▼
Risk of hyperglycemia and hyperosmolar state, phlebitis from hypertonic solution, hyponatremia, electrolyte imbalance, aluminum toxicity in renal impairment, and hypersensitivity reactions. Contraindicated in intracranial/intraspinal hemorrhage, severe dehydration, alcohol withdrawal, and dextrose hypersensitivity.
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Medical Disclaimer
This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.