Diclofenac Epolamine

Generic Name: diclofenac epolamine

Over-the-Counter (OTC)

Brand Names:

Licart

LICART is a 10 cm x 14 cm topical system containing 1.3% diclofenac epolamine (182 mg per patch). The active ingredient is an NSAID presented as a topical adhesive system.

Overview

LICART is a 10 cm x 14 cm topical system containing 1.3% diclofenac epolamine (182 mg per patch). The active ingredient is an NSAID presented as a topical adhesive system.

Uses

Indicated for the topical treatment of acute pain due to minor strains, sprains, and contusions.

Dosage

The recommended dose is one patch applied once daily to the most painful area. Use the lowest effective dose for the shortest duration. Do not apply to damaged or non-intact skin. Avoid bathing or showering while wearing.

Side Effects

Most common reactions are localized application site pruritus and other skin reactions (irritation, erythema, rash, inflammation). Post-marketing reports include serious skin reactions: exfoliative dermatitis, Stevens-Johnson Syndrome, toxic epidermal necrolysis.

Interactions

Significant interactions include anticoagulants (increased bleeding risk), aspirin (GI toxicity risk), ACE inhibitors/ARBs (reduced efficacy, renal deterioration), diuretics, digoxin, lithium, methotrexate, cyclosporine, and pemetrexed.

Warnings

NSAIDs carry warnings regarding serious cardiovascular thrombotic events (myocardial infarction, stroke) that may be fatal, and serious gastrointestinal events (bleeding, ulceration, perforation). Contraindicated post-CABG surgery, with known hypersensitivity, or history of asthma/urticaria after aspirin or NSAIDs.

Pregnancy

Avoid use at approximately 30 weeks gestation and later due to fetal ductus arteriosus closure risk. Between 20-30 weeks, limit to lowest effective dose and shortest duration.

Storage

Store at 20-25 degrees C (68-77 degrees F). After opening the envelope, patches remain stable up to 6 months at room temperature.

Frequently Asked Questions

What is Diclofenac Epolamine used for?▼

Indicated for the topical treatment of acute pain due to minor strains, sprains, and contusions.

What are the side effects of Diclofenac Epolamine?▼

Can I take Diclofenac Epolamine during pregnancy?▼

Avoid use at approximately 30 weeks gestation and later due to fetal ductus arteriosus closure risk. Between 20-30 weeks, limit to lowest effective dose and shortest duration.

What are the important warnings for Diclofenac Epolamine?▼

Related Medications

Dial Antibacterial And Sensitive Deodorant Bar Soap Hypoallergenic Aloe Scent

dial antibacterial and sensitive deodorant bar soap hypoallergenic aloe scent

Purpose Antibacterial

Ondansetron Hcl

ondansetron hcl

11. Description The active ingredient in ondansetron tablets, USP is ondansetron hydrochloride as the dihydrate, the racemic form of ondansetron and a selective blocking agent of the serotonin 5-HT3 receptor type. Chemically it is (±) 1, 2, 3, 9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one, monohydrochloride, dihydrate. It has the following structural formula: The molecular formula is C18H19N3O•HCl•2H2O, representing a molecular weight of 365.9 g/mol.

Icatibant Acetate

icatibant acetate

11 DESCRIPTION FIRAZYR (icatibant) is a synthetic decapeptide with five non-proteinogenic amino acids. The chemical structure of icatibant acetate is presented in Figure 1. Figure 1 Chemical Structure Chemical name: D-Arginyl-L-arginyl-L-prolyl-L[(4R)-4-hydroxyprolyl]-glycyl-L[3-(2-thienyl)alanyl]-L-seryl-D-(1,2,3,4-tetrahydroisoquinolin-3-ylcarbonyl)-L[(3aS,7aS)-octahydroindol-2-ylcarbonyl]-L-arginine, acetate salt FIRAZYR is provided as a sterile, isotonic, and buffered solution of icatibant a

Medical Disclaimer

This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.