Dicyclomine Hydrochloride
Generic Name: dicyclomine hydrochloride
Brand Names:
Dicyclomine Hydrochloride
Dicyclomine hydrochloride is an antispasmodic and anticholinergic (antimuscarinic) agent supplied as a sterile, pyrogen-free aqueous solution for intramuscular injection at 20 mg/2 mL (10 mg/mL) concentration.
Overview
Dicyclomine hydrochloride is an antispasmodic and anticholinergic (antimuscarinic) agent supplied as a sterile, pyrogen-free aqueous solution for intramuscular injection at 20 mg/2 mL (10 mg/mL) concentration.
Uses
Treats functional bowel/irritable bowel syndrome. It functions as an antispasmodic and anticholinergic (antimuscarinic) agent for gastrointestinal conditions.
Dosage
Dosage must be adjusted to individual patient needs. The recommended intramuscular dose is 10 mg to 20 mg four times a day for adults, limited to 1-2 days when oral medication is unavailable.
Side Effects
Common side effects (greater than 5%) include dizziness, dry mouth, blurred vision, nausea, somnolence, asthenia, and nervousness. Clinical trials showed 61% of patients experienced anticholinergic effects.
Interactions
Antiglaucoma agents: anticholinergics antagonize effects and increase intraocular pressure. Other anticholinergics may increase side effects. Antacids interfere with absorption. Absorption of other drugs like digoxin may be affected.
Warnings
Inadvertent intravenous administration risks thrombosis; cardiovascular effects with tachyarrhythmia conditions; heat prostration with decreased sweating; psychosis/delirium in sensitive patients. Contraindicated in infants under 6 months, nursing mothers, unstable cardiovascular status, acute hemorrhage, myasthenia gravis, glaucoma, obstructive uropathy, GI obstruction, severe ulcerative colitis, and reflux esophagitis.
Pregnancy
This drug should be used during pregnancy only if clearly needed. Epidemiologic studies showed no increased malformation risk at doses up to 40 mg/day during first trimester.
Storage
Store at room temperature, preferably below 86 degrees F (30 degrees C). Protect from freezing.
Frequently Asked Questions
What is Dicyclomine Hydrochloride used for?▼
Treats functional bowel/irritable bowel syndrome. It functions as an antispasmodic and anticholinergic (antimuscarinic) agent for gastrointestinal conditions.
What are the side effects of Dicyclomine Hydrochloride?▼
Common side effects (greater than 5%) include dizziness, dry mouth, blurred vision, nausea, somnolence, asthenia, and nervousness. Clinical trials showed 61% of patients experienced anticholinergic effects.
Can I take Dicyclomine Hydrochloride during pregnancy?▼
This drug should be used during pregnancy only if clearly needed. Epidemiologic studies showed no increased malformation risk at doses up to 40 mg/day during first trimester.
What are the important warnings for Dicyclomine Hydrochloride?▼
Inadvertent intravenous administration risks thrombosis; cardiovascular effects with tachyarrhythmia conditions; heat prostration with decreased sweating; psychosis/delirium in sensitive patients. Contraindicated in infants under 6 months, nursing mothers, unstable cardiovascular status, acute hemorrhage, myasthenia gravis, glaucoma, obstructive uropathy, GI obstruction, severe ulcerative colitis, and reflux esophagitis.
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Medical Disclaimer
This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.