Doxepin Hydrochloride
Generic Name: doxepin hydrochloride
Brand Names:
Doxepin Hydrochloride
Doxepin hydrochloride is a dibenzoxepin tricyclic antidepressant used for the treatment of depression and anxiety disorders.
Overview
Doxepin hydrochloride is a dibenzoxepin tricyclic antidepressant used for the treatment of depression and anxiety disorders.
Uses
Recommended for treating psychoneurotic patients with depression and/or anxiety, depression linked to alcoholism or organic disease, and psychotic depressive disorders. Target symptoms include anxiety, tension, depression, sleep disturbances, and worry.
Dosage
Starting daily dose of 75 mg for mild-to-moderate illness; usual range is 75-150 mg/day. Severely ill patients may require up to 300 mg/day. Once-daily dosing maximum is 150 mg at bedtime.
Side Effects
Include drowsiness, dry mouth, blurred vision, constipation, urinary retention, confusion, and cardiovascular effects like hypotension or tachycardia.
Interactions
Doxepin is primarily metabolized by CYP2D6. Interactions with SSRIs, MAO inhibitors, cimetidine, and alcohol are documented.
Warnings
BOXED WARNING: Antidepressants increased the risk of suicidal thinking and behavior in children, adolescents, and young adults. Clinical worsening and suicide risk. Angle-closure glaucoma potential. Contraindicated in patients with glaucoma or a tendency to urinary retention.
Storage
Store at 20-25 degrees C.
Frequently Asked Questions
What is Doxepin Hydrochloride used for?▼
Recommended for treating psychoneurotic patients with depression and/or anxiety, depression linked to alcoholism or organic disease, and psychotic depressive disorders. Target symptoms include anxiety, tension, depression, sleep disturbances, and worry.
What are the side effects of Doxepin Hydrochloride?▼
Include drowsiness, dry mouth, blurred vision, constipation, urinary retention, confusion, and cardiovascular effects like hypotension or tachycardia.
What are the important warnings for Doxepin Hydrochloride?▼
BOXED WARNING: Antidepressants increased the risk of suicidal thinking and behavior in children, adolescents, and young adults. Clinical worsening and suicide risk. Angle-closure glaucoma potential. Contraindicated in patients with glaucoma or a tendency to urinary retention.
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Medical Disclaimer
This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.