Doxorubicin Hydrochloride
Generic Name: doxorubicin hydrochloride
Brand Names:
Doxorubicin Hydrochloride Liposome
Doxorubicin Hydrochloride is a sterile liposomal dispersion containing doxorubicin hydrochloride encapsulated in pegylated liposomes for intravenous use in cancer treatment.
Overview
Doxorubicin Hydrochloride is a sterile liposomal dispersion containing doxorubicin hydrochloride encapsulated in pegylated liposomes for intravenous use in cancer treatment.
Uses
Treatment of ovarian cancer after platinum failure, AIDS-related Kaposi's sarcoma after prior chemotherapy failure or intolerance, and multiple myeloma combined with bortezomib.
Dosage
Ovarian cancer: 50 mg/m2 every 4 weeks. AIDS-KS: 20 mg/m2 every 3 weeks. Multiple myeloma: 30 mg/m2 on day 4 of cycles.
Side Effects
Most common adverse reactions (more than 20%) are asthenia, fatigue, fever, anorexia, nausea, vomiting, stomatitis, diarrhea.
Interactions
No formal drug interaction studies have been conducted.
Warnings
BOXED WARNING: Cardiomyopathy risk of 11% at cumulative doses 450-550 mg/m2. Infusion-related reactions occurring in 11% of patients. Includes cardiomyopathy assessment, infusion reactions, hand-foot syndrome, secondary oral neoplasms, embryo-fetal toxicity. Contraindicated in severe hypersensitivity reactions and anaphylaxis to doxorubicin.
Frequently Asked Questions
What is Doxorubicin Hydrochloride used for?▼
Treatment of ovarian cancer after platinum failure, AIDS-related Kaposi's sarcoma after prior chemotherapy failure or intolerance, and multiple myeloma combined with bortezomib.
What are the side effects of Doxorubicin Hydrochloride?▼
Most common adverse reactions (more than 20%) are asthenia, fatigue, fever, anorexia, nausea, vomiting, stomatitis, diarrhea.
What are the important warnings for Doxorubicin Hydrochloride?▼
BOXED WARNING: Cardiomyopathy risk of 11% at cumulative doses 450-550 mg/m2. Infusion-related reactions occurring in 11% of patients. Includes cardiomyopathy assessment, infusion reactions, hand-foot syndrome, secondary oral neoplasms, embryo-fetal toxicity. Contraindicated in severe hypersensitivity reactions and anaphylaxis to doxorubicin.
Related Medications
Salsolinol
salsolinol
*Claims based on traditional homeopathic practice, not accepted medical evidence. Not FDA evaluated.
Carduus Marianus, Chelidonium Majus, Lappa Major, Uva Ursi, Raphanus Sativus, Taraxacum Officinale, Lycopodium Clavatum, Hydrastis Canadensis, Gallbladder (bovine), Hepar Suis, Beta Vulgaris, Phosphorus
carduus marianus, chelidonium majus, lappa major, uva ursi, raphanus sativus, taraxacum officinale, lycopodium clavatum, hydrastis canadensis, gallbladder (bovine), hepar suis, beta vulgaris, phosphorus
Non-Standardized Food Allergenic Extract [EPC]
PURPOSE: Provides potentized homeo-nutritional support and drainage for the liver.† †Claims based on traditional homeopathic practice, not accepted medical evidence. Not FDA evaluated.
Mag Phos, Erigeron, Nux Mos, Ignatia, Alstonia, China Off, Hydrastis
mag phos, erigeron, nux mos, ignatia, alstonia, china off, hydrastis
Non-Standardized Food Allergenic Extract [EPC]
Uses Temporarily relieves occasional indigestion, gas, bloating, nausea, acidity, a painful and burning sensation in the upper abdominal region, belching, diffuse abdominal discomfort, chest discomfort, and vomiting.* *CLAIMS BASED ON TRADITIONAL HOMEOPATHIC PRACTICE, NOT ACCEPTED MEDICAL EVIDENCE. NOT FDA EVALUATED. This product is not intended to diagnose, treat, cure, or prevent any disease.
Medical Disclaimer
This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.