Doxycycline

Generic Name: doxycycline

Tetracycline-class Drug [EPC]Over-the-Counter (OTC)

Brand Names:

Doxycycline

Doxycycline is a broad-spectrum tetracycline antibiotic synthesized from oxytetracycline, available in 50 mg, 75 mg, or 100 mg capsules.

Overview

Doxycycline is a broad-spectrum tetracycline antibiotic synthesized from oxytetracycline, available in 50 mg, 75 mg, or 100 mg capsules.

Uses

Indicated for treating infections caused by susceptible bacteria including rickettsial infections, respiratory tract infections from Mycoplasma pneumoniae, chlamydial infections, plague, tularemia, cholera, brucellosis, and others. Also used as post-exposure prophylaxis for inhalational anthrax.

Dosage

Adults typically receive 200 mg on day one (100 mg every 12 hours), followed by 100 mg daily maintenance. Pediatric dosing for severe infections: 2.2 mg/kg every 12 hours for children under 45 kg. Take with adequate fluids to reduce esophageal irritation.

Side Effects

Common side effects include gastrointestinal issues like diarrhea and nausea. Serious reactions noted are Stevens-Johnson syndrome, photosensitivity, intracranial hypertension, and C. difficile-associated diarrhea.

Warnings

Risk of permanent tooth discoloration in pediatric patients under 8 years. Intracranial hypertension, photosensitivity, and C. difficile-associated diarrhea are serious concerns. Contraindicated in persons who have shown hypersensitivity to any of the tetracyclines.

Frequently Asked Questions

What is Doxycycline used for?

Indicated for treating infections caused by susceptible bacteria including rickettsial infections, respiratory tract infections from Mycoplasma pneumoniae, chlamydial infections, plague, tularemia, cholera, brucellosis, and others. Also used as post-exposure prophylaxis for inhalational anthrax.

What are the side effects of Doxycycline?

Common side effects include gastrointestinal issues like diarrhea and nausea. Serious reactions noted are Stevens-Johnson syndrome, photosensitivity, intracranial hypertension, and C. difficile-associated diarrhea.

What are the important warnings for Doxycycline?

Risk of permanent tooth discoloration in pediatric patients under 8 years. Intracranial hypertension, photosensitivity, and C. difficile-associated diarrhea are serious concerns. Contraindicated in persons who have shown hypersensitivity to any of the tetracyclines.

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Medical Disclaimer

This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.