Efavirenz, Emtricitabine And Tenofovir Disoproxil Fumarate
Generic Name: efavirenz, emtricitabine and tenofovir disoproxil fumarate
Brand Names:
Efavirenz, Emtricitabine And Tenofovir Disoproxil Fumarate
Efavirenz, emtricitabine, and tenofovir disoproxil fumarate is a fixed-dose combination tablet containing 600 mg efavirenz, 200 mg emtricitabine, and 300 mg tenofovir disoproxil fumarate for HIV-1 treatment.
Overview
Efavirenz, emtricitabine, and tenofovir disoproxil fumarate is a fixed-dose combination tablet containing 600 mg efavirenz, 200 mg emtricitabine, and 300 mg tenofovir disoproxil fumarate for HIV-1 treatment.
Uses
Indicated as a complete regimen or in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults and pediatric patients weighing at least 40 kg.
Dosage
One tablet once daily taken orally on an empty stomach, preferably at bedtime for adults and pediatric patients weighing at least 40 kg.
Side Effects
Most common include diarrhea, nausea, fatigue, headache, dizziness, depression, insomnia, abnormal dreams, and rash.
Interactions
Numerous significant interactions documented with protease inhibitors, anticonvulsants, antifungals, and other medications. Contraindicated with voriconazole or elbasvir/grazoprevir.
Warnings
BOXED WARNING: Severe acute exacerbations of hepatitis B virus (HBV) have been reported in coinfected patients who discontinued products containing emtricitabine and/or tenofovir. Extensive warnings including rash, hepatotoxicity, psychiatric symptoms, renal impairment, embryo-fetal toxicity, and bone mineral density decreases.
Pregnancy
Avoid pregnancy while receiving and for 12 weeks after discontinuation due to potential neural tube defect risk.
Frequently Asked Questions
What is Efavirenz, Emtricitabine And Tenofovir Disoproxil Fumarate used for?▼
Indicated as a complete regimen or in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults and pediatric patients weighing at least 40 kg.
What are the side effects of Efavirenz, Emtricitabine And Tenofovir Disoproxil Fumarate?▼
Most common include diarrhea, nausea, fatigue, headache, dizziness, depression, insomnia, abnormal dreams, and rash.
Can I take Efavirenz, Emtricitabine And Tenofovir Disoproxil Fumarate during pregnancy?▼
Avoid pregnancy while receiving and for 12 weeks after discontinuation due to potential neural tube defect risk.
What are the important warnings for Efavirenz, Emtricitabine And Tenofovir Disoproxil Fumarate?▼
BOXED WARNING: Severe acute exacerbations of hepatitis B virus (HBV) have been reported in coinfected patients who discontinued products containing emtricitabine and/or tenofovir. Extensive warnings including rash, hepatotoxicity, psychiatric symptoms, renal impairment, embryo-fetal toxicity, and bone mineral density decreases.
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Medical Disclaimer
This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.