Enoxaparin Sodium
Generic Name: enoxaparin sodium
Brand Names:
Lovenox
Enoxaparin sodium is a low molecular weight heparin anticoagulant administered as a clear, colorless to pale yellow sterile solution by subcutaneous injection.
Overview
Enoxaparin sodium is a low molecular weight heparin anticoagulant administered as a clear, colorless to pale yellow sterile solution by subcutaneous injection.
Uses
Approved for DVT prophylaxis in abdominal/hip/knee surgery and immobilized medical patients; acute DVT/PE treatment; unstable angina and non-Q-wave MI prophylaxis; acute STEMI management.
Dosage
Varies by indication: 40 mg daily to 1.5 mg/kg daily subcutaneously. Adjusted dosing for renal impairment and geriatric patients 75 years and older.
Side Effects
Bleeding, anemia, thrombocytopenia, elevation of serum aminotransferase, diarrhea, nausea, ecchymosis.
Interactions
Discontinue anticoagulants, antiplatelet agents, NSAIDs, and salicylates before use when possible.
Warnings
BOXED WARNING: Epidural/spinal hematomas with neuraxial anesthesia risk with potential permanent paralysis. Hemorrhage, thrombocytopenia, HIT, and mechanical heart valve concerns. Contraindicated in active major bleeding, HIT history, and hypersensitivity to enoxaparin, heparin, or pork products.
Pregnancy
Data suggest no increased major developmental abnormality risk. Careful monitoring advised.
Frequently Asked Questions
What is Enoxaparin Sodium used for?▼
Approved for DVT prophylaxis in abdominal/hip/knee surgery and immobilized medical patients; acute DVT/PE treatment; unstable angina and non-Q-wave MI prophylaxis; acute STEMI management.
What are the side effects of Enoxaparin Sodium?▼
Bleeding, anemia, thrombocytopenia, elevation of serum aminotransferase, diarrhea, nausea, ecchymosis.
Can I take Enoxaparin Sodium during pregnancy?▼
Data suggest no increased major developmental abnormality risk. Careful monitoring advised.
What are the important warnings for Enoxaparin Sodium?▼
BOXED WARNING: Epidural/spinal hematomas with neuraxial anesthesia risk with potential permanent paralysis. Hemorrhage, thrombocytopenia, HIT, and mechanical heart valve concerns. Contraindicated in active major bleeding, HIT history, and hypersensitivity to enoxaparin, heparin, or pork products.
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Medical Disclaimer
This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.