Entecavir
Generic Name: entecavir
Brand Names:
Entecavir
Entecavir is a nucleoside analogue with selective activity against hepatitis B virus, available as film-coated tablets in 0.5 mg and 1 mg strengths.
Overview
Entecavir is a nucleoside analogue with selective activity against hepatitis B virus, available as film-coated tablets in 0.5 mg and 1 mg strengths.
Uses
Indicated for the treatment of chronic hepatitis B virus infection in adults and pediatric patients 2 years of age and older with evidence of active viral replication.
Dosage
Nucleoside-inhibitor-treatment-naive: 0.5 mg once daily. Lamivudine-refractory: 1 mg once daily. Must be taken on empty stomach (2 hours after or before meals).
Side Effects
Most common are headache, fatigue, dizziness, and nausea.
Interactions
Coadministration with renal-eliminating drugs requires close monitoring. No significant interactions with lamivudine, adefovir, or tenofovir.
Warnings
BOXED WARNING: Severe hepatitis B exacerbations upon discontinuation. HIV resistance risk in co-infected patients not receiving HAART. Lactic acidosis/hepatomegaly risk. Monitor hepatic function closely. Not recommended for HIV/HBV co-infection without HAART.
Frequently Asked Questions
What is Entecavir used for?▼
Indicated for the treatment of chronic hepatitis B virus infection in adults and pediatric patients 2 years of age and older with evidence of active viral replication.
What are the side effects of Entecavir?▼
Most common are headache, fatigue, dizziness, and nausea.
What are the important warnings for Entecavir?▼
BOXED WARNING: Severe hepatitis B exacerbations upon discontinuation. HIV resistance risk in co-infected patients not receiving HAART. Lactic acidosis/hepatomegaly risk. Monitor hepatic function closely. Not recommended for HIV/HBV co-infection without HAART.
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Medical Disclaimer
This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.