Ephedrine Sulfate
Generic Name: ephedrine sulfate
Brand Names:
Ephedrine Sulfate
Ephedrine sulfate is a prescription sympathomimetic amine that directly acts as an agonist at alpha- and beta-adrenergic receptors, used for the treatment of hypotension during anesthesia.
Overview
Ephedrine sulfate is a prescription sympathomimetic amine that directly acts as an agonist at alpha- and beta-adrenergic receptors, used for the treatment of hypotension during anesthesia.
Uses
Indicated for the treatment of clinically important hypotension occurring in the setting of anesthesia.
Dosage
Initial dose of 5-10 mg administered by intravenous bolus, with additional boluses as needed not exceeding 50 mg total. The 50 mg/mL concentration must be diluted before IV administration.
Side Effects
Most common reactions include nausea, vomiting, and tachycardia. Other documented effects encompass cardiac rhythm disturbances, dizziness, and gastrointestinal symptoms.
Interactions
Notable interactions include oxytocic drugs, clonidine, propofol, MAOIs, atropine, alpha/beta-adrenergic antagonists, cardiac glycosides, and theophylline.
Warnings
Serious postpartum hypertension has been described in patients who received both a vasopressor and an oxytocic. Repeated administration of ephedrine can result in tachyphylaxis.
Pregnancy
Available data shows no identified drug-associated risks of major birth defects or miscarriage. Monitoring newborns for metabolic acidosis is warranted.
Storage
Store at 20-25 degrees C (68-77 degrees F) in original carton until use.
Frequently Asked Questions
What is Ephedrine Sulfate used for?▼
Indicated for the treatment of clinically important hypotension occurring in the setting of anesthesia.
What are the side effects of Ephedrine Sulfate?▼
Most common reactions include nausea, vomiting, and tachycardia. Other documented effects encompass cardiac rhythm disturbances, dizziness, and gastrointestinal symptoms.
Can I take Ephedrine Sulfate during pregnancy?▼
Available data shows no identified drug-associated risks of major birth defects or miscarriage. Monitoring newborns for metabolic acidosis is warranted.
What are the important warnings for Ephedrine Sulfate?▼
Serious postpartum hypertension has been described in patients who received both a vasopressor and an oxytocic. Repeated administration of ephedrine can result in tachyphylaxis.
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Medical Disclaimer
This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.