Epinephrine
Generic Name: epinephrine
Brand Names:
Epinephrine
Epinephrine injection is a prescription auto-injector containing epinephrine solution for emergency treatment of severe allergic reactions including anaphylaxis.
Overview
Epinephrine injection is a prescription auto-injector containing epinephrine solution for emergency treatment of severe allergic reactions including anaphylaxis.
Uses
Emergency treatment of allergic reactions (Type I) including anaphylaxis from insect stings/bites, foods, drugs, allergen immunotherapy, and diagnostic substances. Intended for immediate administration in patients at increased risk.
Dosage
Patients 15-30 kg receive 0.15 mg. Inject intramuscularly or subcutaneously into the anterolateral aspect of the thigh, through clothing if necessary. Do not inject intravenously or into buttocks, digits, hands, or feet.
Side Effects
Common effects include anxiety, apprehensiveness, restlessness, tremor, weakness, dizziness, sweating, palpitations. Serious cardiovascular reactions and arrhythmias may occur.
Interactions
Beta-blockers antagonize epinephrine's effects. Tricyclic antidepressants and MAOIs potentiate effects. Cardiac glycosides require monitoring for arrhythmias.
Warnings
Seek immediate medical or hospital care alongside epinephrine use. Avoid intravenous injection. Use caution in patients with heart disease. Risk of serious infections including gas gangrene if injected incorrectly.
Pregnancy
Epinephrine is the first-line medication of choice for treatment of anaphylaxis during pregnancy. Animal studies showed teratogenicity at high doses.
Storage
Store at room temperature (20-25 degrees C / 68-77 degrees F). Protect from light. Replace if discolored or cloudy.
Frequently Asked Questions
What is Epinephrine used for?▼
Emergency treatment of allergic reactions (Type I) including anaphylaxis from insect stings/bites, foods, drugs, allergen immunotherapy, and diagnostic substances. Intended for immediate administration in patients at increased risk.
What are the side effects of Epinephrine?▼
Common effects include anxiety, apprehensiveness, restlessness, tremor, weakness, dizziness, sweating, palpitations. Serious cardiovascular reactions and arrhythmias may occur.
Can I take Epinephrine during pregnancy?▼
Epinephrine is the first-line medication of choice for treatment of anaphylaxis during pregnancy. Animal studies showed teratogenicity at high doses.
What are the important warnings for Epinephrine?▼
Seek immediate medical or hospital care alongside epinephrine use. Avoid intravenous injection. Use caution in patients with heart disease. Risk of serious infections including gas gangrene if injected incorrectly.
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Medical Disclaimer
This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.