Erlotinib Hydrochloride

Generic Name: erlotinib hydrochloride

Over-the-Counter (OTC)

Brand Names:

Erlotinib hydrochloride is a prescription kinase inhibitor (quinazolinamine) available as tablets in 25 mg, 100 mg, and 150 mg strengths for the treatment of certain cancers.

Overview

Erlotinib hydrochloride is a prescription kinase inhibitor (quinazolinamine) available as tablets in 25 mg, 100 mg, and 150 mg strengths for the treatment of certain cancers.

Uses

Treatment of metastatic non-small cell lung cancer (NSCLC) with specific EGFR mutations and first-line treatment of locally advanced, unresectable or metastatic pancreatic cancer.

Dosage

150 mg orally, on an empty stomach, once daily for NSCLC. 100 mg orally, on an empty stomach, once daily for pancreatic cancer combined with gemcitabine.

Side Effects

Most common include rash, diarrhea, fatigue, anorexia, dyspnea, cough, nausea, and vomiting.

Interactions

CYP3A4 inhibitors, inducers, smoking, and gastric pH-altering agents significantly affect erlotinib levels.

Warnings

Includes interstitial lung disease, renal failure, hepatotoxicity, gastrointestinal perforation, skin disorders, and ocular disorders.

Pregnancy

Can cause fetal harm. Advise females to use contraception during and one month after treatment.

Frequently Asked Questions

What is Erlotinib Hydrochloride used for?▼

Treatment of metastatic non-small cell lung cancer (NSCLC) with specific EGFR mutations and first-line treatment of locally advanced, unresectable or metastatic pancreatic cancer.

What are the side effects of Erlotinib Hydrochloride?▼

Most common include rash, diarrhea, fatigue, anorexia, dyspnea, cough, nausea, and vomiting.

Can I take Erlotinib Hydrochloride during pregnancy?▼

Can cause fetal harm. Advise females to use contraception during and one month after treatment.

What are the important warnings for Erlotinib Hydrochloride?▼

Includes interstitial lung disease, renal failure, hepatotoxicity, gastrointestinal perforation, skin disorders, and ocular disorders.

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Medical Disclaimer

This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.