Ertapenem Sodium
Generic Name: ertapenem sodium
Brand Names:
Ertapenem
Ertapenem sodium is a sterile, synthetic carbapenem antibiotic for parenteral administration, indicated for moderate to severe bacterial infections.
Overview
Ertapenem sodium is a sterile, synthetic carbapenem antibiotic for parenteral administration, indicated for moderate to severe bacterial infections.
Uses
Treatment of moderate to severe infections in adults and pediatric patients (3+ months): complicated intra-abdominal infections, skin/skin structure infections, community-acquired pneumonia, urinary tract infections, acute pelvic infections, and surgical site infection prophylaxis for colorectal surgery.
Dosage
Adults/pediatrics 13+: 1 gram daily IV/IM. Ages 3 months-12 years: 15 mg/kg twice daily (max 1 gram/day). IV infusion over 30 minutes for up to 14 days or IM for up to 7 days.
Side Effects
Most common: diarrhea, nausea, headache, infused vein complication in adults. Diarrhea, vomiting, infusion site pain in pediatrics.
Interactions
Probenecid reduces renal clearance. Valproic acid/divalproex sodium interaction increases seizure risk.
Warnings
Hypersensitivity reactions, seizure potential, valproic acid interaction, C. difficile-associated diarrhea. Contraindicated in known hypersensitivity to product components or anaphylactic reactions to beta-lactams, and amide local anesthetic hypersensitivity for IM use.
Pregnancy
Animal studies showed no developmental malformations at therapeutic exposures. Limited human data available.
Frequently Asked Questions
What is Ertapenem Sodium used for?▼
Treatment of moderate to severe infections in adults and pediatric patients (3+ months): complicated intra-abdominal infections, skin/skin structure infections, community-acquired pneumonia, urinary tract infections, acute pelvic infections, and surgical site infection prophylaxis for colorectal surgery.
What are the side effects of Ertapenem Sodium?▼
Most common: diarrhea, nausea, headache, infused vein complication in adults. Diarrhea, vomiting, infusion site pain in pediatrics.
Can I take Ertapenem Sodium during pregnancy?▼
Animal studies showed no developmental malformations at therapeutic exposures. Limited human data available.
What are the important warnings for Ertapenem Sodium?▼
Hypersensitivity reactions, seizure potential, valproic acid interaction, C. difficile-associated diarrhea. Contraindicated in known hypersensitivity to product components or anaphylactic reactions to beta-lactams, and amide local anesthetic hypersensitivity for IM use.
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Medical Disclaimer
This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.