Felodipine
Generic Name: felodipine
Brand Names:
Felodipine
Felodipine is a calcium channel blocker available as extended-release tablets in 2.5 mg, 5 mg, and 10 mg strengths for oral administration.
Overview
Felodipine is a calcium channel blocker available as extended-release tablets in 2.5 mg, 5 mg, and 10 mg strengths for oral administration.
Uses
Treatment of hypertension, may be used alone or with other antihypertensive agents.
Dosage
Starting dose 5 mg once daily; range 2.5-10 mg daily. Swallow whole, do not crush or chew.
Side Effects
Most common: peripheral edema and headache; dose and age dependent. Also flushing, dizziness, palpitations reported.
Interactions
CYP3A4 inhibitors increase felodipine levels. Grapefruit juice increases AUC/Cmax 2-fold. Itraconazole causes 8-fold AUC increase.
Warnings
May precipitate hypotension, syncope, or reflex tachycardia. Caution with heart failure. Peripheral edema occurs in 10-30% depending on age/dose. Contraindicated with hypersensitivity to this product.
Pregnancy
Category C. Digital anomalies in rabbit fetuses at doses as low as 0.8x human dose. Not studied adequately in pregnant women. Unknown if secreted in human milk.
Storage
Store 20-25C; excursions permitted 15-30C. Protect from light. Tight, light-resistant container.
Frequently Asked Questions
What is Felodipine used for?▼
Treatment of hypertension, may be used alone or with other antihypertensive agents.
What are the side effects of Felodipine?▼
Most common: peripheral edema and headache; dose and age dependent. Also flushing, dizziness, palpitations reported.
Can I take Felodipine during pregnancy?▼
Category C. Digital anomalies in rabbit fetuses at doses as low as 0.8x human dose. Not studied adequately in pregnant women. Unknown if secreted in human milk.
What are the important warnings for Felodipine?▼
May precipitate hypotension, syncope, or reflex tachycardia. Caution with heart failure. Peripheral edema occurs in 10-30% depending on age/dose. Contraindicated with hypersensitivity to this product.
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Medical Disclaimer
This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.