Finasteride
Generic Name: finasteride
Brand Names:
Finasteride
Finasteride is a synthetic 4-azasteroid compound and specific inhibitor of steroid Type II 5-alpha-reductase, an intracellular enzyme that converts testosterone into dihydrotestosterone (DHT).
Overview
Finasteride is a synthetic 4-azasteroid compound and specific inhibitor of steroid Type II 5-alpha-reductase, an intracellular enzyme that converts testosterone into dihydrotestosterone (DHT).
Uses
Indicated for treatment of symptomatic benign prostatic hyperplasia (BPH) in men with enlarged prostate to improve symptoms, reduce the risk of acute urinary retention, and reduce the risk of the need for surgery. Also indicated with alpha-blocker doxazosin to reduce BPH symptom progression.
Dosage
One tablet (5 mg) taken once a day for monotherapy or combination therapy with doxazosin. May be administered with or without meals.
Side Effects
Most frequent drug-related adverse reactions reported at 1% or greater include: impotence, decreased libido, decreased ejaculate volume, breast enlargement, breast tenderness and rash.
Interactions
No drug interactions of clinical importance have been identified.
Warnings
May increase the risk of high-grade prostate cancer. Reduces PSA levels by approximately 50%, so any confirmed PSA increase should be evaluated. Females should not handle crushed or broken finasteride tablets when they are pregnant. Not for pediatric patients or females.
Pregnancy
Finasteride is contraindicated in pregnant females. May cause abnormalities of external genitalia in male fetus. Pregnant females should not handle crushed or broken tablets due to absorption risk.
Storage
Store at 20 to 25C (68 to 77F). Protect from light and keep container tightly closed.
Frequently Asked Questions
What is Finasteride used for?▼
Indicated for treatment of symptomatic benign prostatic hyperplasia (BPH) in men with enlarged prostate to improve symptoms, reduce the risk of acute urinary retention, and reduce the risk of the need for surgery. Also indicated with alpha-blocker doxazosin to reduce BPH symptom progression.
What are the side effects of Finasteride?▼
Most frequent drug-related adverse reactions reported at 1% or greater include: impotence, decreased libido, decreased ejaculate volume, breast enlargement, breast tenderness and rash.
Can I take Finasteride during pregnancy?▼
Finasteride is contraindicated in pregnant females. May cause abnormalities of external genitalia in male fetus. Pregnant females should not handle crushed or broken tablets due to absorption risk.
What are the important warnings for Finasteride?▼
May increase the risk of high-grade prostate cancer. Reduces PSA levels by approximately 50%, so any confirmed PSA increase should be evaluated. Females should not handle crushed or broken finasteride tablets when they are pregnant. Not for pediatric patients or females.
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Medical Disclaimer
This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.