Fluticasone Propionate And Salmeterol
Generic Name: fluticasone propionate and salmeterol
Brand Names:
Fluticasone Propionate And Salmeterol Diskus
Fluticasone propionate and salmeterol DISKUS is a combination inhalation powder containing a corticosteroid and a long-acting beta-2 adrenergic agonist for oral inhalation in the treatment of asthma and COPD.
Overview
Fluticasone propionate and salmeterol DISKUS is a combination inhalation powder containing a corticosteroid and a long-acting beta-2 adrenergic agonist for oral inhalation in the treatment of asthma and COPD.
Uses
Indicated for twice-daily treatment of asthma in patients aged 4 years and older, and maintenance treatment of airflow obstruction in COPD patients. Not indicated for relief of acute bronchospasm.
Dosage
1 inhalation twice daily by oral inhalation route only. For asthma ages 12+: 100/50, 250/50, or 500/50 mcg based on severity. Ages 4-11: 100/50 mcg. For COPD: 250/50 mcg. Patient should rinse mouth with water without swallowing after inhalation.
Side Effects
Most common include upper respiratory tract infection, pharyngitis, dysphonia, oral candidiasis, bronchitis, cough, headaches, nausea and vomiting in asthma patients. In COPD: pneumonia, oral candidiasis, throat irritation, dysphonia, viral respiratory infections.
Interactions
Strong CYP3A4 inhibitors not recommended (ritonavir, ketoconazole). Monoamine oxidase inhibitors and tricyclic antidepressants: use with extreme caution. Beta-blockers may block bronchodilatory effects. Non-potassium-sparing diuretics may worsen hypokalemia.
Warnings
LABA monotherapy increases the risk of serious asthma-related events. Do not initiate in acutely deteriorating asthma or COPD. Potential for paradoxical bronchospasm, candida infection, pneumonia risk in COPD patients, immunosuppression concerns. Contraindicated for primary treatment of status asthmaticus. Severe hypersensitivity to milk proteins is a contraindication.
Pregnancy
Insufficient data on fluticasone propionate/salmeterol in pregnant women. Animal studies show teratogenicity at high doses. Pregnant women should be closely monitored and medication adjusted as necessary to maintain optimal asthma control.
Frequently Asked Questions
What is Fluticasone Propionate And Salmeterol used for?▼
Indicated for twice-daily treatment of asthma in patients aged 4 years and older, and maintenance treatment of airflow obstruction in COPD patients. Not indicated for relief of acute bronchospasm.
What are the side effects of Fluticasone Propionate And Salmeterol?▼
Most common include upper respiratory tract infection, pharyngitis, dysphonia, oral candidiasis, bronchitis, cough, headaches, nausea and vomiting in asthma patients. In COPD: pneumonia, oral candidiasis, throat irritation, dysphonia, viral respiratory infections.
Can I take Fluticasone Propionate And Salmeterol during pregnancy?▼
Insufficient data on fluticasone propionate/salmeterol in pregnant women. Animal studies show teratogenicity at high doses. Pregnant women should be closely monitored and medication adjusted as necessary to maintain optimal asthma control.
What are the important warnings for Fluticasone Propionate And Salmeterol?▼
LABA monotherapy increases the risk of serious asthma-related events. Do not initiate in acutely deteriorating asthma or COPD. Potential for paradoxical bronchospasm, candida infection, pneumonia risk in COPD patients, immunosuppression concerns. Contraindicated for primary treatment of status asthmaticus. Severe hypersensitivity to milk proteins is a contraindication.
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Pcmx
pcmx
Purpose Antiseptic
Medical Disclaimer
This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.