Folic Acid

Generic Name: folic acid

Over-the-Counter (OTC)

Brand Names:

Folic Acid

Folic acid is a B complex vitamin containing pteridine linked to para-aminobenzoic acid joined to glutamic acid, available as an oral solution for the treatment of megaloblastic anemias due to folic acid deficiency.

Overview

Folic acid is a B complex vitamin containing pteridine linked to para-aminobenzoic acid joined to glutamic acid, available as an oral solution for the treatment of megaloblastic anemias due to folic acid deficiency.

Uses

Indicated for treatment of megaloblastic anemias due to folic acid deficiency in adult and pediatric patients.

Dosage

Initial: up to 1 mg daily. Maintenance varies by age - infants 0.1 mg daily, toddlers 0.3 mg daily, older children/adults 0.4 mg daily, pregnant/lactating women 0.8 mg daily. Use oral dosing syringe for accurate measurement.

Side Effects

Most common: nausea, anorexia, bloating. Also reported: rash, itching, malaise, bronchospasm, GI distress, neurological effects, decreased B12 levels.

Interactions

Antagonizes phenytoin effectiveness. Multiple drugs reduce folate absorption including anticonvulsants, antibiotics, methotrexate. Separate administration timing recommended.

Warnings

Folic acid in doses above 0.1 mg daily may obscure pernicious anemia while neurologic manifestations progress, potentially causing severe nerve damage. Rule out vitamin B12 deficiency before initiating therapy. Contraindicated in patients with hypersensitivity to folic acid or product ingredients.

Pregnancy

Decades of use have not identified drug-associated risk of major birth defects or miscarriage. First-trimester deficiency increases neural tube defect risk. Pregnant/lactating women require 0.8 mg daily.

Storage

Store at 20-25 degrees C (68-77 degrees F). Store in original amber container protected from light. Discard 30 days after opening.

Frequently Asked Questions

What is Folic Acid used for?

Indicated for treatment of megaloblastic anemias due to folic acid deficiency in adult and pediatric patients.

What are the side effects of Folic Acid?

Most common: nausea, anorexia, bloating. Also reported: rash, itching, malaise, bronchospasm, GI distress, neurological effects, decreased B12 levels.

Can I take Folic Acid during pregnancy?

Decades of use have not identified drug-associated risk of major birth defects or miscarriage. First-trimester deficiency increases neural tube defect risk. Pregnant/lactating women require 0.8 mg daily.

What are the important warnings for Folic Acid?

Folic acid in doses above 0.1 mg daily may obscure pernicious anemia while neurologic manifestations progress, potentially causing severe nerve damage. Rule out vitamin B12 deficiency before initiating therapy. Contraindicated in patients with hypersensitivity to folic acid or product ingredients.

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Medical Disclaimer

This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.