Lidocaine Hydrochloride And Epinephrine
Generic Name: lidocaine hydrochloride and epinephrine
Brand Names:
Lidocaine Hydrochloride And Epinephrine
Lidocaine hydrochloride and epinephrine is a sterile, nonpyrogenic solution for parenteral administration indicated for production of local or regional anesthesia for surgery, dental, oral surgery, diagnostic, therapeutic, and obstetrical procedures.
Overview
Lidocaine hydrochloride and epinephrine is a sterile, nonpyrogenic solution for parenteral administration indicated for production of local or regional anesthesia for surgery, dental, oral surgery, diagnostic, therapeutic, and obstetrical procedures.
Uses
Indicated in adult and pediatric patients for production of local or regional anesthesia for surgery, dental, oral surgery, diagnostic, therapeutic, and obstetrical procedures.
Dosage
Dosage varies with anesthetic procedure, area anesthetized, vascularity, neuronal segments blocked, anesthesia depth, muscle relaxation needed, and duration desired. Administer smallest dosage producing desired result. Maximum: 7 mg/kg with epinephrine (500 mg total) for adults.
Side Effects
CNS effects: lightheadedness, nervousness, confusion, dizziness, drowsiness, tremors, convulsions, respiratory depression. Cardiovascular: bradycardia, hypotension, collapse. Allergic reactions: urticaria, edema, anaphylaxis. Methemoglobinemia reported.
Interactions
Local anesthetics: additive toxic effects. MAOIs/tricyclic antidepressants: severe hypertension risk. Ergot oxytocics: severe hypertension/cerebrovascular accident risk. Nonselective beta-blockers: hypertension/bradycardia. Oxidizing agents: methemoglobinemia. Potent inhalation anesthetics: cardiac arrhythmias.
Warnings
Monitor cardiovascular/respiratory vital signs. Dose-related toxicity risk. Methemoglobinemia possible. Avoid intra-articular infusions. Sulfite allergies may cause reactions. Risk with unintended intravascular/intrathecal injection. Hepatic impairment increases toxicity risk. Contraindicated in patients with known hypersensitivity to lidocaine or amide-type local anesthetics.
Pregnancy
Available data and decades of clinical use have not identified drug-associated risks for major birth defects or miscarriage. Published data report low amounts of lidocaine in human milk with poor oral bioavailability.
Storage
Store at 20-25 degrees C (68-77 degrees F). Protect from light. Do not autoclave. Discard unused portions of single-dose vials.
Frequently Asked Questions
What is Lidocaine Hydrochloride And Epinephrine used for?▼
Indicated in adult and pediatric patients for production of local or regional anesthesia for surgery, dental, oral surgery, diagnostic, therapeutic, and obstetrical procedures.
What are the side effects of Lidocaine Hydrochloride And Epinephrine?▼
CNS effects: lightheadedness, nervousness, confusion, dizziness, drowsiness, tremors, convulsions, respiratory depression. Cardiovascular: bradycardia, hypotension, collapse. Allergic reactions: urticaria, edema, anaphylaxis. Methemoglobinemia reported.
Can I take Lidocaine Hydrochloride And Epinephrine during pregnancy?▼
Available data and decades of clinical use have not identified drug-associated risks for major birth defects or miscarriage. Published data report low amounts of lidocaine in human milk with poor oral bioavailability.
What are the important warnings for Lidocaine Hydrochloride And Epinephrine?▼
Monitor cardiovascular/respiratory vital signs. Dose-related toxicity risk. Methemoglobinemia possible. Avoid intra-articular infusions. Sulfite allergies may cause reactions. Risk with unintended intravascular/intrathecal injection. Hepatic impairment increases toxicity risk. Contraindicated in patients with known hypersensitivity to lidocaine or amide-type local anesthetics.
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Medical Disclaimer
This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.