Loteprednol Etabonate
Generic Name: loteprednol etabonate
Brand Names:
Loteprednol Etabonate
Loteprednol etabonate is a sterile topical anti-inflammatory corticosteroid for ophthalmic use containing 0.5% loteprednol etabonate, indicated for steroid-responsive inflammatory conditions of the eye.
Overview
Loteprednol etabonate is a sterile topical anti-inflammatory corticosteroid for ophthalmic use containing 0.5% loteprednol etabonate, indicated for steroid-responsive inflammatory conditions of the eye.
Uses
Indicated for steroid-responsive inflammatory conditions including allergic conjunctivitis, acne rosacea, keratitis, iritis, and post-operative inflammation.
Dosage
Apply one to two drops into conjunctival sac four times daily. May increase to 1 drop hourly during first week if needed.
Side Effects
Common reactions (5-15%): blurring, burning, chemosis, discharge, dry eyes. Less common: elevated intraocular pressure, posterior subcapsular cataract, secondary infections.
Warnings
Prolonged use may result in glaucoma, visual defects, cataracts. Risk of secondary infections. May exacerbate viral infections including herpes simplex. Contraindicated in viral diseases (herpes simplex, vaccinia, varicella), mycobacterial and fungal infections, and hypersensitivity to ingredients.
Pregnancy
Pregnancy Category C: Animal studies showed embryotoxicity and teratogenicity at doses significantly higher than clinical doses. Unknown if systemic absorption occurs during nursing; caution advised.
Storage
Store upright between 15-25 degrees C (59-77 degrees F). Do not freeze. Keep protective seal intact.
Frequently Asked Questions
What is Loteprednol Etabonate used for?▼
Indicated for steroid-responsive inflammatory conditions including allergic conjunctivitis, acne rosacea, keratitis, iritis, and post-operative inflammation.
What are the side effects of Loteprednol Etabonate?▼
Common reactions (5-15%): blurring, burning, chemosis, discharge, dry eyes. Less common: elevated intraocular pressure, posterior subcapsular cataract, secondary infections.
Can I take Loteprednol Etabonate during pregnancy?▼
Pregnancy Category C: Animal studies showed embryotoxicity and teratogenicity at doses significantly higher than clinical doses. Unknown if systemic absorption occurs during nursing; caution advised.
What are the important warnings for Loteprednol Etabonate?▼
Prolonged use may result in glaucoma, visual defects, cataracts. Risk of secondary infections. May exacerbate viral infections including herpes simplex. Contraindicated in viral diseases (herpes simplex, vaccinia, varicella), mycobacterial and fungal infections, and hypersensitivity to ingredients.
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Medical Disclaimer
This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.