Norepinephrine Bitartrate
Generic Name: norepinephrine bitartrate
Brand Names:
Norepinephrine Bitartrate In Sodium Chloride
Norepinephrine bitartrate is a catecholamine supplied as a sterile IV solution indicated to raise blood pressure in adult patients with severe, acute hypotension.
Overview
Norepinephrine bitartrate is a catecholamine supplied as a sterile IV solution indicated to raise blood pressure in adult patients with severe, acute hypotension.
Uses
Indicated to raise blood pressure in adult patients with severe, acute hypotension. Used for restoration of blood pressure in acute hypotensive states.
Dosage
Initiate 8 to 12 mcg/min IV infusion, adjust rate to maintain vital organ perfusion. Average maintenance dose 2 to 4 mcg/min. Reduce infusion gradually upon discontinuation.
Side Effects
Most common: hypertension and bradycardia. Also: anxiety, headache, respiratory difficulty, pulmonary edema, ischemic injury, extravasation necrosis.
Interactions
MAOIs/tricyclic antidepressants may cause severe hypertension. Decreases insulin sensitivity. Halogenated anesthetics increase cardiac arrhythmia risk.
Warnings
Risk of tissue ischemia from extravasation. Hypotension after abrupt discontinuation. Cardiac arrhythmias. Avoid leg veins in elderly. Address hypovolemia before use.
Pregnancy
Limited human data shows no increased birth defect risk. Animal studies at high doses showed decreased placental blood flow and fetal abnormalities.
Storage
Store 20-25 degrees C (68-77 degrees F) in original carton to protect from light. Use within 7 days of overwrap removal. Do not freeze.
Frequently Asked Questions
What is Norepinephrine Bitartrate used for?▼
Indicated to raise blood pressure in adult patients with severe, acute hypotension. Used for restoration of blood pressure in acute hypotensive states.
What are the side effects of Norepinephrine Bitartrate?▼
Most common: hypertension and bradycardia. Also: anxiety, headache, respiratory difficulty, pulmonary edema, ischemic injury, extravasation necrosis.
Can I take Norepinephrine Bitartrate during pregnancy?▼
Limited human data shows no increased birth defect risk. Animal studies at high doses showed decreased placental blood flow and fetal abnormalities.
What are the important warnings for Norepinephrine Bitartrate?▼
Risk of tissue ischemia from extravasation. Hypotension after abrupt discontinuation. Cardiac arrhythmias. Avoid leg veins in elderly. Address hypovolemia before use.
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Medical Disclaimer
This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.