Olmesartan Medoxomil And Hydrochlorothiazide
Generic Name: olmesartan medoxomil and hydrochlorothiazide
Brand Names:
Olmesartan Medoxomil And Hydrochlorothiazide
Combination tablet containing olmesartan medoxomil (angiotensin II receptor antagonist) and hydrochlorothiazide (thiazide diuretic) for the treatment of hypertension.
Overview
Combination tablet containing olmesartan medoxomil (angiotensin II receptor antagonist) and hydrochlorothiazide (thiazide diuretic) for the treatment of hypertension.
Uses
Indicated for the treatment of hypertension, to lower blood pressure. Not indicated for initial therapy of hypertension.
Dosage
Starting dose of 40/12.5 mg once daily for patients inadequately controlled on olmesartan alone, or 20/12.5 mg once daily for those on hydrochlorothiazide alone. Maximum dose is 40/25 mg.
Side Effects
Most common adverse reactions (incidence 2% or greater): nausea, hyperuricemia, dizziness, and upper respiratory infection. Serious reactions include sprue-like enteropathy with chronic diarrhea and angle-closure glaucoma.
Interactions
Dual blockade of the RAS with angiotensin receptor blockers, ACE inhibitors, or aliskiren is associated with increased risks of hypotension, hyperkalemia, and changes in renal function.
Warnings
Fetal toxicity: Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus. When pregnancy is detected, discontinue as soon as possible. Additional concerns include hypotension, renal impairment, electrolyte imbalances, and acute myopia.
Pregnancy
Significant fetal risks exist, particularly during the second and third trimesters of pregnancy. Discontinuation is mandatory upon pregnancy detection.
Storage
Store at 20-25 degrees C (68-77 degrees F).
Frequently Asked Questions
What is Olmesartan Medoxomil And Hydrochlorothiazide used for?▼
Indicated for the treatment of hypertension, to lower blood pressure. Not indicated for initial therapy of hypertension.
What are the side effects of Olmesartan Medoxomil And Hydrochlorothiazide?▼
Most common adverse reactions (incidence 2% or greater): nausea, hyperuricemia, dizziness, and upper respiratory infection. Serious reactions include sprue-like enteropathy with chronic diarrhea and angle-closure glaucoma.
Can I take Olmesartan Medoxomil And Hydrochlorothiazide during pregnancy?▼
Significant fetal risks exist, particularly during the second and third trimesters of pregnancy. Discontinuation is mandatory upon pregnancy detection.
What are the important warnings for Olmesartan Medoxomil And Hydrochlorothiazide?▼
Fetal toxicity: Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus. When pregnancy is detected, discontinue as soon as possible. Additional concerns include hypotension, renal impairment, electrolyte imbalances, and acute myopia.
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Medical Disclaimer
This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.