Omeprazole And Sodium Bicarbonate
Generic Name: omeprazole and sodium bicarbonate
Brand Names:
Omeprazole/bicarbonate
Combination of omeprazole (proton-pump inhibitor) and sodium bicarbonate (antacid) in capsule form. Reduces gastric acid production for the treatment of various gastrointestinal conditions.
Overview
Combination of omeprazole (proton-pump inhibitor) and sodium bicarbonate (antacid) in capsule form. Reduces gastric acid production for the treatment of various gastrointestinal conditions.
Uses
Treatment of active duodenal ulcer, benign gastric ulcer, symptomatic gastroesophageal reflux disease (GERD), erosive esophagitis, and maintenance healing of erosive esophagitis.
Dosage
20-40 mg omeprazole once daily. Dosage varies by indication (4-12 weeks). Take intact capsule on empty stomach one hour before meals.
Side Effects
Common: headache, abdominal pain, nausea, diarrhea, vomiting, flatulence. Serious: acute tubulointerstitial nephritis, C. difficile-associated diarrhea, bone fractures with long-term use.
Interactions
Avoid clopidogrel, rilpivirine, St. John's wort, rifampin. Monitor warfarin, methotrexate, and multiple CYP2C19 substrates.
Warnings
Monitor for gastric malignancy. Consider bone health with long-term use. Risk of vitamin B-12 deficiency with prolonged use. Contains 304 mg sodium per capsule. Contraindicated with rilpivirine-containing products and in patients with known hypersensitivity to benzimidazoles.
Pregnancy
Available epidemiologic data fail to demonstrate increased risk with first trimester omeprazole use. Insufficient data for sodium bicarbonate component.
Frequently Asked Questions
What is Omeprazole And Sodium Bicarbonate used for?▼
Treatment of active duodenal ulcer, benign gastric ulcer, symptomatic gastroesophageal reflux disease (GERD), erosive esophagitis, and maintenance healing of erosive esophagitis.
What are the side effects of Omeprazole And Sodium Bicarbonate?▼
Common: headache, abdominal pain, nausea, diarrhea, vomiting, flatulence. Serious: acute tubulointerstitial nephritis, C. difficile-associated diarrhea, bone fractures with long-term use.
Can I take Omeprazole And Sodium Bicarbonate during pregnancy?▼
Available epidemiologic data fail to demonstrate increased risk with first trimester omeprazole use. Insufficient data for sodium bicarbonate component.
What are the important warnings for Omeprazole And Sodium Bicarbonate?▼
Monitor for gastric malignancy. Consider bone health with long-term use. Risk of vitamin B-12 deficiency with prolonged use. Contains 304 mg sodium per capsule. Contraindicated with rilpivirine-containing products and in patients with known hypersensitivity to benzimidazoles.
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Medical Disclaimer
This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.