Oxybutynin Chloride
Generic Name: oxybutynin chloride
Brand Names:
Oxybutynin Chloride Extended Release
Oxybutynin chloride is an antispasmodic, muscarinic antagonist available in extended-release tablets for once-daily oral administration in the treatment of overactive bladder.
Overview
Oxybutynin chloride is an antispasmodic, muscarinic antagonist available in extended-release tablets for once-daily oral administration in the treatment of overactive bladder.
Uses
Treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency. Also indicated for pediatric patients aged 6 and older with detrusor overactivity associated with neurological conditions like spina bifida.
Dosage
Adults start with 5-10 mg once daily, with a maximum of 30 mg per day. Pediatric patients aged 6 and older start with 5 mg once daily, with a maximum of 20 mg per day. Tablets must be swallowed whole and adjusted in 5 mg increments weekly.
Side Effects
Most common adverse effects include dry mouth, constipation, diarrhea, headache, somnolence, and dizziness. Discontinuation rate was 4.4% due to adverse effects.
Interactions
CYP3A4 inhibitors increase systemic exposure. Anticholinergic combinations may amplify effects.
Warnings
Risk of angioedema and CNS effects. Use with caution in patients with urinary retention risk, decreased GI motility, and bladder obstruction. Caution advised for patients with dementia, Parkinson's disease, and myasthenia gravis. Contraindicated in patients with uncontrolled narrow-angle glaucoma.
Pregnancy
No adequate data available. Unknown background risks for indicated population.
Frequently Asked Questions
What is Oxybutynin Chloride used for?▼
Treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency. Also indicated for pediatric patients aged 6 and older with detrusor overactivity associated with neurological conditions like spina bifida.
What are the side effects of Oxybutynin Chloride?▼
Most common adverse effects include dry mouth, constipation, diarrhea, headache, somnolence, and dizziness. Discontinuation rate was 4.4% due to adverse effects.
Can I take Oxybutynin Chloride during pregnancy?▼
No adequate data available. Unknown background risks for indicated population.
What are the important warnings for Oxybutynin Chloride?▼
Risk of angioedema and CNS effects. Use with caution in patients with urinary retention risk, decreased GI motility, and bladder obstruction. Caution advised for patients with dementia, Parkinson's disease, and myasthenia gravis. Contraindicated in patients with uncontrolled narrow-angle glaucoma.
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Medical Disclaimer
This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.