Oxycodone And Acetaminophen

Generic Name: oxycodone and acetaminophen

Over-the-Counter (OTC)

Brand Names:

Prolate

Oxycodone hydrochloride and acetaminophen tablets are available for oral administration in three strengths (5/300 mg, 7.5/300 mg, 10/300 mg) for the treatment of severe pain requiring opioid analgesia.

Overview

Uses

Treatment of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate.

Dosage

Dosage should be individualized based on severity of pain, patient response, and prior analgesic experience. Use the lowest effective dose for the shortest duration consistent with treatment goals.

Side Effects

Common adverse reactions include nausea, vomiting, constipation, lightheadedness, dizziness, and sedation. Serious risks include respiratory depression, addiction, and hepatotoxicity.

Interactions

Significant interactions with CYP3A4 inhibitors and inducers, benzodiazepines and other CNS depressants, serotonergic drugs, and MAO inhibitors. Concurrent use may increase or decrease opioid effects.

Warnings

Serious and life-threatening risks including addiction, abuse, and misuse. Risk of respiratory depression. Accidental ingestion can cause fatal overdose. Dangerous interactions with CNS depressants including benzodiazepines. Risk of neonatal opioid withdrawal syndrome. Hepatotoxicity risk from acetaminophen component.

Pregnancy

Prolonged use during pregnancy can result in neonatal opioid withdrawal syndrome. Oxycodone present in breast milk at low levels.

Frequently Asked Questions

What is Oxycodone And Acetaminophen used for?▼

Treatment of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate.

What are the side effects of Oxycodone And Acetaminophen?▼

Common adverse reactions include nausea, vomiting, constipation, lightheadedness, dizziness, and sedation. Serious risks include respiratory depression, addiction, and hepatotoxicity.

Can I take Oxycodone And Acetaminophen during pregnancy?▼

Prolonged use during pregnancy can result in neonatal opioid withdrawal syndrome. Oxycodone present in breast milk at low levels.

What are the important warnings for Oxycodone And Acetaminophen?▼

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Medical Disclaimer

This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.