Permethrin
Generic Name: permethrin
Brand Names:
Permethrin
DESCRIPTION: Permethrin Cream, 5% is a topical scabicidal agent for the treatment of infestation with Sarcoptes scabiei (scabies). It is available in an off-white, greaseless, uniform mass. Permethrin Cream, 5% is for topical use only. Chemical Name - The permethrin used is an approximate 1:3 mixture of the cis and trans isomers of the pyrethroid 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid, (3-phenoxyphenyl) methyl ester.
Overview
DESCRIPTION: Permethrin Cream, 5% is a topical scabicidal agent for the treatment of infestation with Sarcoptes scabiei (scabies). It is available in an off-white, greaseless, uniform mass. Permethrin Cream, 5% is for topical use only. Chemical Name - The permethrin used is an approximate 1:3 mixture of the cis and trans isomers of the pyrethroid 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid, (3-phenoxyphenyl) methyl ester.
Uses
INDICATIONS AND USAGE: Permethrin Cream, 5% is indicated for the treatment of infestation with Sarcoptes scabiei (scabies).
Dosage
DOSAGE AND ADMINISTRATION: Adults and Children - Thoroughly massage Permethrin Cream, 5% into the skin from the head to the soles of the feet. Scabies rarely infests the scalp of adults, although the hairline, neck, temple, and forehead may be infested in infants and geriatric patients. Usually 30 grams is sufficient for an average adult. The cream should be removed by washing (shower or bath) after 8 to 14 hours. Infants should be treated on the scalp, temple, and forehead. ONE APPLICATION IS GENERALLY CURATIVE. Patients may experience persistent pruritus after treatment. This is rarely a sign of treatment failure and is not an indication for retreatment. Demonstrable living mites after 14 days indicate that retreatment is necessary.
Side Effects
ADVERSE REACTIONS: In clinical trials, generally mild and transient burning and stinging followed application with Permethrin Cream, 5% in 10% of patients and was associated with the severity of infestation. Pruritus was reported in 7% of patients at various times post-application. Erythema, numbness, tingling, and rash were reported in 1 to 2% or less of patients (see PRECAUTIONS: General ). Other adverse events reported since marketing Permethrin Cream, 5% include: headache, fever, dizziness, abdominal pain, diarrhea and nausea and/or vomiting. Although extremely uncommon and not expected when used as directed (see DOSAGE AND ADMINISTRATION ), rare occurrences of seizure have been reported. None have been medically confirmed as associated with Permethrin Cream, 5% treatment.
Warnings
WARNINGS: If hypersensitivity to Permethrin Cream, 5% occurs, discontinue use. CONTRAINDICATIONS: Permethrin Cream, 5% is contraindicated in patients with known hypersensitivity to any of its components, to any synthetic pyrethroid or pyrethrin.
Pregnancy
Pregnancy - Reproduction studies have been performed in mice, rats, and rabbits (200 to 400 mg/kg/day orally) and have revealed no evidence of impaired fertility or harm to the fetus due to permethrin. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.
Storage
HOW SUPPLIED: Permethrin Cream, 5% contains 50 mg permethrin per gram. The off-white, greaseless, uniform mass is available as follows: Carton containing one 60 g tube NDC 84386-073-60 STORAGE: Store at 20° to 25°C (68° to 77°F) [see USP Controlled Room Temperature.] Distributed by: Aurobindo Pharma USA, Inc.
Frequently Asked Questions
What is Permethrin used for?▼
INDICATIONS AND USAGE: Permethrin Cream, 5% is indicated for the treatment of infestation with Sarcoptes scabiei (scabies).
What are the side effects of Permethrin?▼
ADVERSE REACTIONS: In clinical trials, generally mild and transient burning and stinging followed application with Permethrin Cream, 5% in 10% of patients and was associated with the severity of infestation. Pruritus was reported in 7% of patients at various times post-application. Erythema, numbness, tingling, and rash were reported in 1 to 2% or less of patients (see PRECAUTIONS: General ). Other adverse events reported since marketing Permethrin Cream, 5% include: headache, fever, dizziness, abdominal pain, diarrhea and nausea and/or vomiting. Although extremely uncommon and not expected when used as directed (see DOSAGE AND ADMINISTRATION ), rare occurrences of seizure have been reported. None have been medically confirmed as associated with Permethrin Cream, 5% treatment.
Can I take Permethrin during pregnancy?▼
Pregnancy - Reproduction studies have been performed in mice, rats, and rabbits (200 to 400 mg/kg/day orally) and have revealed no evidence of impaired fertility or harm to the fetus due to permethrin. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.
What are the important warnings for Permethrin?▼
WARNINGS: If hypersensitivity to Permethrin Cream, 5% occurs, discontinue use. CONTRAINDICATIONS: Permethrin Cream, 5% is contraindicated in patients with known hypersensitivity to any of its components, to any synthetic pyrethroid or pyrethrin.
Related Medications
Flurbiprofen
flurbiprofen
Nonsteroidal Anti-inflammatory Drug [EPC]
11 DESCRIPTION Flurbiprofen Tablets, USP are a member of the phenylalkanoic acid derivative group of nonsteroidal anti-inflammatory drug. Flurbiprofen Tablets, USP are round, blue, film-coated debossed "NH" – "100" tablets for oral administration. Flurbiprofen, USP is a racemic mixture of (+)S- and (-)R- enantiomers. Flurbiprofen, USP is a white or slightly yellow crystalline powder. It is slightly soluble in water at pH 7.0 and readily soluble in most polar solvents.
Phytolacca Decandra, Thuja Occidentalis
phytolacca decandra, thuja occidentalis
Purpose Phytolacca decandra - 15C HPUS (for warts), Thuja occidentalis -15C HPUS (locally for warts) The letters ‘HPUS’ indicate that the components in this product are officially monographed in the Homoeopathic Pharmacopoeia of the United States
Belladonna, Bryonia, Cimicifuga, Gelsemium, Glonoinum, Ignatia, Iris Vers, Nux Vom, Sanguinaria, Sepia, Spigelia Anth
belladonna, bryonia, cimicifuga, gelsemium, glonoinum, ignatia, iris vers, nux vom, sanguinaria, sepia, spigelia anth
Nitrate Vasodilator [EPC]
Temporarily relieves migraine headache symptoms* *Claims based on traditional homeopathic practice, not accepted medical evidence. Not FDA evaluated.
Medical Disclaimer
This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.