Prochlorperazine Edisylate
Generic Name: prochlorperazine edisylate
Brand Names:
Prochlorperazine Edisylate
Prochlorperazine edisylate is a sterile injection solution for intramuscular or intravenous use, containing 5 mg prochlorperazine per mL as the edisylate salt.
Overview
Prochlorperazine edisylate is a sterile injection solution for intramuscular or intravenous use, containing 5 mg prochlorperazine per mL as the edisylate salt.
Uses
Treatment of severe nausea and vomiting, and management of schizophrenia.
Dosage
For nausea and vomiting, intramuscular dosing is 5 to 10 mg injected deeply into the upper outer quadrant of the buttock every 3-4 hours, not exceeding 40 mg daily.
Side Effects
Common effects include drowsiness, dizziness, and hypotension. Serious risks include neuroleptic malignant syndrome, tardive dyskinesia, and extrapyramidal reactions.
Warnings
Elderly patients with dementia-related psychosis treated with antipsychotics face increased risk of death, with mortality rates 1.6 to 1.7 times higher than placebo. Risk of tardive dyskinesia and neuroleptic malignant syndrome. Contraindicated in patients under age 2 or under 20 lbs.
Frequently Asked Questions
What is Prochlorperazine Edisylate used for?▼
Treatment of severe nausea and vomiting, and management of schizophrenia.
What are the side effects of Prochlorperazine Edisylate?▼
Common effects include drowsiness, dizziness, and hypotension. Serious risks include neuroleptic malignant syndrome, tardive dyskinesia, and extrapyramidal reactions.
What are the important warnings for Prochlorperazine Edisylate?▼
Elderly patients with dementia-related psychosis treated with antipsychotics face increased risk of death, with mortality rates 1.6 to 1.7 times higher than placebo. Risk of tardive dyskinesia and neuroleptic malignant syndrome. Contraindicated in patients under age 2 or under 20 lbs.
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Medical Disclaimer
This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.