Rosuvastatin Calcium
Generic Name: rosuvastatin calcium
Brand Names:
Rosuvastatin Calcium
Rosuvastatin calcium is a synthetic lipid-lowering agent (HMG-CoA reductase inhibitor/statin) for oral administration used to treat high cholesterol and reduce cardiovascular risk.
Overview
Rosuvastatin calcium is a synthetic lipid-lowering agent (HMG-CoA reductase inhibitor/statin) for oral administration used to treat high cholesterol and reduce cardiovascular risk.
Uses
Treatment of hypertriglyceridemia, primary dysbetalipoproteinemia, and homozygous familial hypercholesterolemia as adjunctive therapy to diet.
Dosage
Dose range: 5 to 40 mg once daily. Use 40 mg dose only for patients not reaching LDL-C goal with 20 mg.
Side Effects
Most frequent adverse reactions include headache, myalgia, abdominal pain, asthenia, and nausea.
Interactions
Multiple significant interactions including cyclosporine and protease inhibitors. Dose adjustments may be needed with concomitant medications.
Warnings
Skeletal muscle effects including myopathy and rhabdomyolysis. Risks increase with use of 40 mg dose and advanced age (65 and older). Contraindicated in active liver disease, pregnancy, and lactation.
Pregnancy
Contraindicated in pregnancy. Rosuvastatin calcium may cause fetal harm when administered to pregnant women.
Frequently Asked Questions
What is Rosuvastatin Calcium used for?▼
Treatment of hypertriglyceridemia, primary dysbetalipoproteinemia, and homozygous familial hypercholesterolemia as adjunctive therapy to diet.
What are the side effects of Rosuvastatin Calcium?▼
Most frequent adverse reactions include headache, myalgia, abdominal pain, asthenia, and nausea.
Can I take Rosuvastatin Calcium during pregnancy?▼
Contraindicated in pregnancy. Rosuvastatin calcium may cause fetal harm when administered to pregnant women.
What are the important warnings for Rosuvastatin Calcium?▼
Skeletal muscle effects including myopathy and rhabdomyolysis. Risks increase with use of 40 mg dose and advanced age (65 and older). Contraindicated in active liver disease, pregnancy, and lactation.
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Medical Disclaimer
This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.