Sevelamer Carbonate
Generic Name: sevelamer carbonate
Brand Names:
Sevelamer Carbonate
Sevelamer carbonate is a polymeric amine phosphate binder for oral administration, functioning as an anion exchange resin for the control of serum phosphorus in patients with chronic kidney disease on dialysis.
Overview
Sevelamer carbonate is a polymeric amine phosphate binder for oral administration, functioning as an anion exchange resin for the control of serum phosphorus in patients with chronic kidney disease on dialysis.
Uses
Indicated for the control of serum phosphorus in adults with chronic kidney disease (CKD) on dialysis.
Dosage
Starting dose is 0.8-1.6 grams three times daily with meals. Titrate by 0.8 g increments every two weeks based on serum phosphorus levels.
Side Effects
Most common effects include vomiting (22%), nausea (20%), diarrhea (19%), dyspepsia (16%), abdominal pain (9%), flatulence (8%), and constipation (8%).
Interactions
May reduce bioavailability of ciprofloxacin and mycophenolate mofetil. Separate dosing is recommended.
Warnings
Serious cases of dysphagia, bowel obstruction, and perforation have been associated with sevelamer use. Contraindicated in patients with bowel obstruction or hypersensitivity to sevelamer carbonate.
Frequently Asked Questions
What is Sevelamer Carbonate used for?▼
Indicated for the control of serum phosphorus in adults with chronic kidney disease (CKD) on dialysis.
What are the side effects of Sevelamer Carbonate?▼
Most common effects include vomiting (22%), nausea (20%), diarrhea (19%), dyspepsia (16%), abdominal pain (9%), flatulence (8%), and constipation (8%).
What are the important warnings for Sevelamer Carbonate?▼
Serious cases of dysphagia, bowel obstruction, and perforation have been associated with sevelamer use. Contraindicated in patients with bowel obstruction or hypersensitivity to sevelamer carbonate.
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Medical Disclaimer
This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.