Trihexyphenidyl Hydrochloride
Generic Name: trihexyphenidyl hydrochloride
Brand Names:
Trihexyphenidyl Hydrochloride
DESCRIPTION Trihexyphenidyl hydrochloride Tablets, USP is a synthetic antispasmodic drug available in the following forms: Tablets, 2 mg and 5 mg. It is designated chemically 1-Piperidinepropanol,α-cyclohexyl-α-phenyl-, hydrochloride. The structural formula is represented below: Trihexyphenidyl Hydrochloride Tablets, USP 2 mg and 5 mg contain the following inactive ingredients: Microcrystalline cellulose, magnesium stearate and sodium starch glycolate. structure
Overview
DESCRIPTION Trihexyphenidyl hydrochloride Tablets, USP is a synthetic antispasmodic drug available in the following forms: Tablets, 2 mg and 5 mg. It is designated chemically 1-Piperidinepropanol,α-cyclohexyl-α-phenyl-, hydrochloride. The structural formula is represented below: Trihexyphenidyl Hydrochloride Tablets, USP 2 mg and 5 mg contain the following inactive ingredients: Microcrystalline cellulose, magnesium stearate and sodium starch glycolate. structure
Uses
INDICATIONS & USAGE This drug is indicated as an adjunct in the treatment of all forms of parkinsonism (postencephalitic, arteriosclerotic, and idiopathic). It is often useful as adjuvant therapy when treating these forms of parkinsonism with levodopa. Additionally, it is indicated for the control of extrapyramidal disorders caused by central nervous system drugs such as the dibenzoxazepines, phenothiazines, thioxanthenes, and butyrophenones.
Dosage
DOSAGE & ADMINISTRATION Dosage should be individualized. The initial dose should be low and then increased gradually, especially in patients over 60 years of age. Whether trihexyphenidyl hydrochloride may best be given before or after meals should be determined by the way the patient reacts. Postencephalitic patients, who are usually more prone to excessive salivation, may prefer to take it after meals and may, in addition, require small amounts of atropine which, under such circumstances, is sometimes an effective adjuvant. If trihexyphenidyl hydrochloride tends to dry the mouth excessively, it may be better to take it before meals, unless it causes nausea. If taken after meals, the thirst sometimes induced can be allayed by mint candies, chewing gum or water.
Side Effects
ADVERSE REACTIONS Minor side effects, such as dryness of the mouth, blurring of vision, dizziness, mild nausea, or nervousness, will be experienced by 30 to 50 percent of all patients. These sensations, however, are much less troublesome with trihexyphenidyl hydrochloride than with belladonna alkaloids and are usually less disturbing than unalleviated parkinsonism. Such reactions tend to become less pronounced, and even to disappear, as treatment continues. Even before these reactions have remitted spontaneously, they may often be controlled by careful adjustment of the dosage form, amount of drug, or interval between doses.
Warnings
WARNINGS Patients to be treated with trihexyphenidyl hydrochloride should have a gonioscope evaluation and close monitoring of intraocular pressures at regular periodic intervals.
Storage
HOW SUPPLIED Trihexyphenidyl Hydrochloride Tablets, USP 2 mg are available as white, flat face, beveled edge and round. The upper layer is bisected and debossed "212/N" , the lower layer is plain: NDC: 70518-2410-00 NDC: 70518-2410-01 NDC: 70518-2410-02 NDC: 70518-2410-03 NDC: 70518-2410-04 NDC: 70518-2410-05 PACKAGING: 100 in 1 BOX PACKAGING: 1 in 1 POUCH PACKAGING: 30 in 1 BLISTER PACK PACKAGING...
Frequently Asked Questions
What is Trihexyphenidyl Hydrochloride used for?▼
INDICATIONS & USAGE This drug is indicated as an adjunct in the treatment of all forms of parkinsonism (postencephalitic, arteriosclerotic, and idiopathic). It is often useful as adjuvant therapy when treating these forms of parkinsonism with levodopa. Additionally, it is indicated for the control of extrapyramidal disorders caused by central nervous system drugs such as the dibenzoxazepines, phenothiazines, thioxanthenes, and butyrophenones.
What are the side effects of Trihexyphenidyl Hydrochloride?▼
ADVERSE REACTIONS Minor side effects, such as dryness of the mouth, blurring of vision, dizziness, mild nausea, or nervousness, will be experienced by 30 to 50 percent of all patients. These sensations, however, are much less troublesome with trihexyphenidyl hydrochloride than with belladonna alkaloids and are usually less disturbing than unalleviated parkinsonism. Such reactions tend to become less pronounced, and even to disappear, as treatment continues. Even before these reactions have remitted spontaneously, they may often be controlled by careful adjustment of the dosage form, amount of drug, or interval between doses.
What are the important warnings for Trihexyphenidyl Hydrochloride?▼
WARNINGS Patients to be treated with trihexyphenidyl hydrochloride should have a gonioscope evaluation and close monitoring of intraocular pressures at regular periodic intervals.
Related Medications
Kali Muriaticum, Carbo Vegetabilis, Lung (suis), Mycoplasma Pneumoniae, Bryonia (alba), Gelsemium Sempervirens, Haemophilus Influenzae B, Pneumococcinum, Oxygenium, Antimonium Arsenicicum, Camphora, Chelidonium Majus, Chininum Muriaticum, Cuprum Metallicum, Ipecacuanha, Lobelia Purpurescens, Phosphorus, Senega Officinalis, Stannum Metallicum, Veratrum Viride
kali muriaticum, carbo vegetabilis, lung (suis), mycoplasma pneumoniae, bryonia (alba), gelsemium sempervirens, haemophilus influenzae b, pneumococcinum, oxygenium, antimonium arsenicicum, camphora, chelidonium majus, chininum muriaticum, cuprum metallicum, ipecacuanha, lobelia purpurescens, phosphorus, senega officinalis, stannum metallicum, veratrum viride
Copper-containing Intrauterine Device [EPC]
HOMEOPATHIC INDICATIONS: For temporary relief of symptoms related to drainage of lungs such as fatigue and cough.** **These statements are based upon homeopathic principles. They have not been reviewed by the Food and Drug Administration.
Doconexent, Niacinamide, .alpha.-tocopherol Acetate, Dl-, Cholecalciferol, .beta.-carotene, Ascorbic Acid, Thiamine Mononitrate, Riboflavin, Pyridoxine Hydrochloride, Cyanocobalamin, Iron, Zinc Oxide, Cupric Oxide, Potassium Iodide, Magnesium Oxide, Folic Acid, And Levomefolate Calcium
doconexent, niacinamide, .alpha.-tocopherol acetate, dl-, cholecalciferol, .beta.-carotene, ascorbic acid, thiamine mononitrate, riboflavin, pyridoxine hydrochloride, cyanocobalamin, iron, zinc oxide, cupric oxide, potassium iodide, magnesium oxide, folic acid, and levomefolate calcium
Vitamin C [EPC]
COMPOSITION Amount per Capsule: VITAMINS AND MINERALS: Vitamin A (as beta carotene) 330 mcg RAE Vitamin C (as ascorbic acid) 30 mg Vitamin D (as cholecalciferol) 25 mcg Vitamin E (as dl-alpha tocopheryl acetate) 9 mg Thiamin (Vitamin B1 as thiamine mononitrate) 1.6 mg Riboflavin (Vitamin B2) 1.8 mg Niacin (as niacinamide) 15 mg NE Vitamin B6 (as pyridoxine hydrochloride) 2.5 mg Folate (680 mcg DFE from folic acid & 1020 mcg DFE from l-methylfolate calcium) 1700 mcg DFE Vitamin B12 (as cyanocobal
Tezacaftor And Ivacaftor
tezacaftor and ivacaftor
11 DESCRIPTION SYMDEKO is co-packaged as a tezacaftor/ivacaftor fixed-dose combination tablet and an ivacaftor tablet. Both tablets are for oral administration. Tezacaftor 50 mg/ivacaftor 75 mg fixed-dose combination tablets and ivacaftor 75 mg tablets : The tezacaftor/ivacaftor fixed-dose combination tablet is available as a white, oblong-shaped, film-coated tablet containing 50 mg of tezacaftor, 75 mg of ivacaftor, and the following inactive ingredients: croscarmellose sodium, hypromellose, hy
Medical Disclaimer
This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.