Cyclosporine
Generic Name: cyclosporine
Brand Names:
Verkazia
Verkazia ophthalmic emulsion is a sterile, unpreserved topical emulsion appearing as milky-white homogeneous emulsion. Contains cyclosporine 1 mg/mL as active ingredient. A calcineurin inhibitor immunosuppressant.
Overview
Verkazia ophthalmic emulsion is a sterile, unpreserved topical emulsion appearing as milky-white homogeneous emulsion. Contains cyclosporine 1 mg/mL as active ingredient. A calcineurin inhibitor immunosuppressant.
Uses
Verkazia ophthalmic emulsion is indicated for treatment of vernal keratoconjunctivitis (VKC) in children and adults.
Dosage
Instill one drop of Verkazia, 4 times daily (morning, noon, afternoon, and evening) in each affected eye. Gently shake single-dose vial before use. Remove contact lenses before application; may reinsert 15 minutes after.
Side Effects
Most common adverse reactions were eye pain (12%) and eye pruritus (8%), usually transitory during instillation. Other reactions: ocular discomfort (6%), reduced visual acuity (5%), ocular hyperemia (4%), cough (5%), headache (4%).
Warnings
Advise patients not to touch vial tip to eye or other surfaces to avoid potential for eye injury or contamination.
Pregnancy
No adequate well-controlled studies in pregnant women. Animal studies at clinically relevant doses showed no teratogenicity; higher doses produced adverse effects.
Storage
Store at 20 to 25 degrees C (68 to 77 degrees F). Do not freeze. Keep vials in pouch after opening to protect from light and evaporation.
Frequently Asked Questions
What is Cyclosporine used for?▼
Verkazia ophthalmic emulsion is indicated for treatment of vernal keratoconjunctivitis (VKC) in children and adults.
What are the side effects of Cyclosporine?▼
Most common adverse reactions were eye pain (12%) and eye pruritus (8%), usually transitory during instillation. Other reactions: ocular discomfort (6%), reduced visual acuity (5%), ocular hyperemia (4%), cough (5%), headache (4%).
Can I take Cyclosporine during pregnancy?▼
No adequate well-controlled studies in pregnant women. Animal studies at clinically relevant doses showed no teratogenicity; higher doses produced adverse effects.
What are the important warnings for Cyclosporine?▼
Advise patients not to touch vial tip to eye or other surfaces to avoid potential for eye injury or contamination.
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Medical Disclaimer
This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.