Omega-3-acid Ethyl Esters
Generic Name: omega-3-acid ethyl esters
Brand Names:
Omega-3-acid Ethyl Esters
Lipid-regulating agent supplied as liquid-filled gel capsules containing at least 900 mg omega-3 fatty acid ethyl esters per 1-gram capsule, primarily EPA (approximately 465 mg) and DHA (approximately 375 mg).
Overview
Lipid-regulating agent supplied as liquid-filled gel capsules containing at least 900 mg omega-3 fatty acid ethyl esters per 1-gram capsule, primarily EPA (approximately 465 mg) and DHA (approximately 375 mg).
Uses
Indicated as an adjunct to diet to reduce triglyceride levels in adult patients with severe (500 mg/dL or greater) hypertriglyceridemia.
Dosage
The daily dose is 4 grams per day taken as a single 4-gram dose (4 capsules) or as two 2-gram doses (2 capsules given twice daily). Swallow capsules whole without breaking, crushing, or dissolving.
Side Effects
Most common reactions include eructation, dyspepsia, and taste perversion. Other possible effects: constipation, gastrointestinal issues, vomiting, increased liver enzymes, rash, and anaphylactic reactions.
Interactions
May prolong bleeding time. Use caution with anticoagulants or antiplatelet agents. No significant interactions with simvastatin, atorvastatin, or rosuvastatin.
Warnings
Monitor liver function (ALT/AST) in hepatic impairment. LDL levels may increase. Use caution with fish or shellfish allergies. Possible increased atrial fibrillation recurrence. Contraindicated in patients with known hypersensitivity to omega-3-acid ethyl esters.
Pregnancy
Insufficient human data. Animal studies showed no adverse effects at doses up to 5 times the recommended human dose. Omega-3 fatty acids pass into breast milk.
Storage
Store at 20 to 25 degrees C (68 to 77 degrees F). Do not freeze. Keep out of reach of children. Protect from light.
Frequently Asked Questions
What is Omega-3-acid Ethyl Esters used for?▼
Indicated as an adjunct to diet to reduce triglyceride levels in adult patients with severe (500 mg/dL or greater) hypertriglyceridemia.
What are the side effects of Omega-3-acid Ethyl Esters?▼
Most common reactions include eructation, dyspepsia, and taste perversion. Other possible effects: constipation, gastrointestinal issues, vomiting, increased liver enzymes, rash, and anaphylactic reactions.
Can I take Omega-3-acid Ethyl Esters during pregnancy?▼
Insufficient human data. Animal studies showed no adverse effects at doses up to 5 times the recommended human dose. Omega-3 fatty acids pass into breast milk.
What are the important warnings for Omega-3-acid Ethyl Esters?▼
Monitor liver function (ALT/AST) in hepatic impairment. LDL levels may increase. Use caution with fish or shellfish allergies. Possible increased atrial fibrillation recurrence. Contraindicated in patients with known hypersensitivity to omega-3-acid ethyl esters.
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Medical Disclaimer
This drug information is for educational purposes only and should not replace professional medical advice. Drug information is sourced from the FDA National Drug Code Directory and Structured Product Labeling. Always consult with a healthcare provider before starting, stopping, or changing any medication.