Drug & Medication Database

11 DESCRIPTION Pegfilgrastim-bmez is a covalent conjugate of recombinant methionyl human G-CSF and monomethoxypolyethylene glycol. Recombinant methionyl human G-CSF is a water-soluble 175 amino acid protein with a molecular weight of approximately 19 kilodaltons (kD). Recombinant methionyl human G-CSF is obtained from the bacterial fermentation of a strain of E coli transformed with a genetically engineered plasmid containing the human G-CSF gene.

Brands: Ziextenzo

11 DESCRIPTION Pegfilgrastim-cbqv is a covalent conjugate of recombinant methionyl human G-CSF and monomethoxypolyethylene glycol. Recombinant methionyl human G-CSF is a water-soluble, 175 amino acid protein with a molecular weight of approximately 19 kilodaltons (kDa). Recombinant methionyl human G-CSF is obtained from the bacterial fermentation of a strain of E coli transformed with a genetically engineered plasmid containing the human G-CSF gene.

Brands: Udenyca

11 DESCRIPTION Pegfilgrastim-jmdb is a covalent conjugate of recombinant methionyl human G-CSF and monomethoxypolyethylene glycol. Recombinant methionyl human G-CSF is a water-soluble 175 amino acid protein with a molecular weight of approximately 19 kilodaltons (kD). Recombinant methionyl human G-CSF is obtained from the bacterial fermentation of a strain of E coli transformed with a genetically engineered plasmid containing the human G-CSF gene.

Brands: Fulphila

11 DESCRIPTION Pegfilgrastim-unne is a covalent conjugate of recombinant methionyl human G-CSF and monomethoxypolyethylene glycol. Recombinant methionyl human G-CSF is a water-soluble 175 amino acid protein with a molecular weight of approximately 19 kilodaltons (kD). Recombinant methionyl human G-CSF is obtained from the bacterial fermentation of a strain of E coli transformed with a genetically engineered plasmid containing the human G-CSF gene.

Brands: Armlupeg

11 DESCRIPTION Pegfilgrastim-fpgk is a covalent conjugate of recombinant methionyl human G-CSF and monomethoxypolyethylene glycol. Recombinant methionyl human G-CSF is a water-soluble 175 amino acid protein with a molecular weight of approximately 19 kilodaltons (kD). Recombinant methionyl human G-CSF is obtained from the bacterial fermentation of a strain of E coli transformed with a genetically engineered plasmid containing the human G-CSF gene.

Brands: Stimufend

Manufactured by TAKEDA PHARMS USA. Dosage form: SOLUTION. Route: INTRAVENOUS, SUBCUTANEOUS. Active ingredients: PEGINESATIDE ACETATE (EQ 1MG BASE/0.5ML (EQ 1MG BASE/0.5ML)). Application: NDA202799.

11 DESCRIPTION Peginterferon alfa-2a, is a covalent conjugate of recombinant alfa-2a interferon (approximate molecular weight [MW] 20,000 daltons) with a single branched bis-monomethoxy polyethylene glycol (PEG) chain (approximate MW 40,000 daltons). The PEG moiety is linked at a single site to the interferon alfa moiety via a stable amide bond to lysine. Peginterferon alfa-2a has an approximate molecular weight of 60,000 daltons.

Brands: Pegasys

Manufactured by SCHERING. Dosage form: VIAL. Active ingredients: PEGINTERFERON ALFA-2B (50UG/0.5ML). Application: BLA103949.

11 DESCRIPTION Peginterferon beta-1a is a covalent conjugate of recombinant interferon beta-1a (approximate molecular weight [MW] 20,000 daltons) with a single, linear methoxy poly(ethyleneglycol)-O-2-methylpropionaldehyde molecule (approximate MW 20,000 daltons). Interferon beta-1a is produced as a glycosylated protein using genetically-engineered Chinese hamster ovary cells into which the human interferon beta gene has been introduced.

Brands: Plegridy Pen, Plegridy

11 DESCRIPTION Pegloticase is a uric acid specific enzyme which is a PEGylated product that consists of recombinant modified mammalian urate oxidase (uricase) produced by a genetically modified strain of Escherichia coli. Uricase is covalently conjugated to monomethoxypoly (ethylene glycol) [mPEG] (10 kDa molecular weight). The cDNA coding for uricase is based on mammalian sequences. Each uricase subunit has a molecular weight of approximately 34 kDa per subunit.

Brands: Krystexxa

11 DESCRIPTION LUMISIGHT (pegulicianine for injection) is an optical imaging agent for intravenous use. The chemical name of pegulicianine acetate is N-[6-(1-{2-[3,6-bis(2,3-dihydro-1H-indol-1-yl)xanthylium-9-yl]benzene-1-sulfonyl}piperidine-4-carboxamido)hexanoyl]glycylglycyl-L-arginyl-N6-(6-{2-[(1E,3E,5Z)-5-(1-ethyl-3,3-dimethyl-5-sulfonato-1,3-dihydro-2H-indol-2-ylidene)penta-1,3-dien-1-yl]-3,3-dimethyl-5-sulfonato-3H-indol-1-ium-1-yl}hexanoyl)-Llysyl-[2-(2-aminoethoxy)ethoxy]acetyl-S-[(3RS)-

Brands: Lumisight

Dosage form: INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION. Active ingredients: PEGULICIANINE ACETATE (39 mg/4mL). Category: DRUG FOR FURTHER PROCESSING.

11 DESCRIPTION Pegunigalsidase alfa-iwxj, a hydrolytic lysosomal neutral glycosphingolipid-specific enzyme, is a PEGylated and crosslinked, chemically modified, recombinant human alpha-galactosidase A enzyme that is produced by genetically modified Bright Yellow 2 ( Nicotiana tabacum ) plant cells.

Brands: Elfabrio

Dosage form: LIQUID. Active ingredients: PEGVALIASE (20 mg/mL). Category: DRUG FOR FURTHER PROCESSING.

Dosage form: INJECTION, SOLUTION. Active ingredients: PEGVALIASE (5 mg/mL). Category: DRUG FOR FURTHER PROCESSING.

11 DESCRIPTION Pegvisomant is an analog of human growth hormone (GH) of recombinant DNA origin that acts as a GH receptor antagonist. It contains 191 amino acid residues. The molecular weight of pegvisomant is 22 kDa. The molecular weight of the PEG portion of pegvisomant is approximately 5 kDa. The predominant molecular weights of pegvisomant are thus approximately 42, 47, and 52 kDa.

Brands: Somavert

Manufactured by IMMEDICA PHARMA AB. Dosage form: Injectable. Route: Injection. Active ingredients: PEGZILARGINASE-NBLN (0.1MG/KG). Application: BLA761211.

Purpose Shortens duration and reduces severity of symptoms associated with common colds and throat/nasal/bronchial irritations: congestion, cough, hoarseness, sore throat.

Brands: Umcka Menthol

Purpose Temporarily relieves flu symptoms. Shortens duration and reduces severity of symptoms associated with the common cold and throat/nasal/bronchial irritations: chills/fever, chest congestion, nasal congestion, cough, headache, hoarseness, body aches, sneezing/runny nose, sore throat.

Brands: Sambucus Cold Flu Relief Elderberry

Purpose Temporarily relieves allergy and sinus symptoms. Shortens duration and reduces severity of symptoms associated with the common cold and throat, nasal, bronchial irritations: cough, headache, hoarseness, sore throat, sinus pressure, chest congestion, nasal congestion, sneezing/runny nose, shrinks swollen nasal membranes, promotes sinus drainage, burning, itchy eyes, helps decongest sinus openings and passages.

Brands: Allergy And Sinus Relief

Purpose Shortens duration and reduces severity of upper respiratory symptoms

Brands: Natures Way Cold Relief Hot Drink Lemon Flavored

Purpose Shortens duration/reduces severity of upper respiratory symptoms Pain reliever/fever reducer Cough suppressant Sneezing/runny nose/sore throat Nasal decongestant

Brands: Natures Way Cold Flu Relief Fastactives Berry Flavored

Purpose Shortens duration and reduces severity of upper respiratory symptoms

Brands: Natures Way Cold Relief Hot Drink

Purpose Shortens duration and reduces severity of symptoms associated with the common cold and throat/nasal/bronchial irritations, and temporarily relieves flu symptoms: chills/fever, congestion/stuffy nose, cough, headache, hoarseness, minor aches/pains, sneezing/runny nose, sore throat.

Brands: Vclear Berry Dissolving Tablets

Purpose Shortens duration and reduces severity of upper respiratory symptoms Pain reliever/fever reducer++ Cough suppressant++ Sneezing/runny nose/sore throat++ Nasal decongestant++

Brands: Sambucus Cold Flu Relief Hot Drink Lemon Flavored

Purpose Purpose and Indications

Brands: Umcka Fastactv Berry

11 DESCRIPTION Pembrolizumab is a programmed death receptor-1 (PD 1)-blocking antibody. Pembrolizumab is a humanized monoclonal IgG4 kappa antibody with an approximate molecular weight of 149 kDa. Pembrolizumab is produced in recombinant Chinese hamster ovary (CHO) cells. KEYTRUDA (pembrolizumab) injection is a sterile, preservative-free, clear to slightly opalescent, colorless to slightly yellow solution for intravenous use. Each vial contains 100 mg of pembrolizumab in 4 mL of solution.

Brands: Keytruda

Dosage form: INJECTION, SOLUTION. Active ingredients: BERAHYALURONIDASE ALFA (2000 U/mL); PEMBROLIZUMAB (165 mg/mL). Category: DRUG FOR FURTHER PROCESSING.

11 DESCRIPTION KEYTRUDA QLEX is a fixed-combination drug product containing pembrolizumab and berahyaluronidase alfa. Pembrolizumab is a programmed death receptor-1 (PD 1)-blocking antibody. Pembrolizumab is a humanized monoclonal IgG4 kappa antibody with an approximate molecular weight of 149 kDa. Pembrolizumab is produced in recombinant Chinese hamster ovary (CHO) cells.

Brands: Keytruda Qlex

11 DESCRIPTION Pemetrexed is a folate analog metabolic inhibitor. Pemetrexed diacid, the drug substance, has the chemical name N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glumatic acid. The molecular formula is C 20 H 21 N 5 O 6 and the molecular weight is 427.41. The structural formula is as follows: PEMFEXY (pemetrexed injection) for intravenous use is a sterile, clear, colorless to yellow or green-yellow solution .

Brands: Pemfexy