Drug & Medication Database

Manufactured by PARKE DAVIS. Dosage form: TABLET. Route: ORAL. Active ingredients: LIOTRIX (T4 (0.06MG); T3) (0.015MG). Application: NDA016680.

TRADITIONALLY USED FOR: Nausea, motion sickness improved by fresh air*

Brands: Tabacum 200ck

Manufactured by SHIONOGI INC. Dosage form: CAPSULE. Route: ORAL. Active ingredients: TACRINE HYDROCHLORIDE (EQ 20MG BASE). Application: NDA020070.

DESCRIPTION Tacrolimus ointment contains tacrolimus, a macrolide immunosuppressant produced by Streptomyces tsukubaensis . It is for topical dermatologic use only. Chemically, tacrolimus is designated as [3 S- [3 R * [ E (1 S * ,3 S * ,4 S * )],4 S * ,5 R * ,8 S * ,9 E ,12 R * ,14 R * ,15 S * ,16 R * ,18 S * ,19 S * ,26a R * ]]-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-

Brands: Tacrolimus

11 DESCRIPTION Tacrolimus is the active ingredient in ASTAGRAF XL. Tacrolimus is a calcineurin-inhibitor immunosuppressant produced by Streptomyces tsukubaensis . Chemically, tacrolimus is designated as [3 S – [3 R *[ E (1 S *, 3 S *, 4 S *)], 4 S *, 5 R *, 8 S *, 9 E , 12 R *, 14 R *, 15 S *, 16 R *, 18 S *, 19 S *, 26a R *]] – 5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a – hexadecahydro – 5, 19 – dihydroxy – 3 – [2 – (4 – hydroxy – 3 – methoxycyclo – hexyl) – 1 – methylethenyl]

Brands: Astagraf Xl

Dosage form: POWDER. Active ingredients: TACROLIMUS ANHYDROUS (1 kg/kg). Category: BULK INGREDIENT.

Dosage form: POWDER. Active ingredients: TACROLIMUS (1 g/g). Category: BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING.

DESCRIPTION Tacrolimus ointment contains tacrolimus, a macrolide immunosuppressant produced by Streptomyces tsukubaensis . It is for topical dermatologic use only. Chemically, tacrolimus is designated as [3 S -[3 R *[ E (1 S *,3 S *,4 S *)],4 S *,5 R *,8 S *,9 E ,12 R *,14 R *,15 S *,16 R *,18 S *,19 S *, 26a R *]]-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3- methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)

Brands: Tacrolimus

Dosage form: POWDER. Active ingredients: TACROLIMUS (1 kg/kg). Category: BULK INGREDIENT.

11 DESCRIPTION Tadalafil USP is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). Tadalafil has the empirical formula C 22 H 19 N 3 O 4 representing a molecular weight of 389.41. The structural formula is: The chemical designation is pyrazino[1′,2′:1,6]pyrido[3,4-b]indole-1,4-dione,6-(1,3-benzodioxol-5-yl)2,3,6,7,12,12a-hexahydro-2-methyl-,(6R,12aR)-.

Brands: Tadalafil

Dosage form: GRANULE. Active ingredients: TADALAFIL (1 kg/kg). Category: BULK INGREDIENT.

Dosage form: POWDER. Active ingredients: TADALAFIL (1 kg/kg). Category: BULK INGREDIENT.

11. DESCRIPTION VYNDAQEL (tafamidis meglumine) and VYNDAMAX (tafamidis) contain tafamidis as the active moiety, which is a selective stabilizer of transthyretin. The chemical name of tafamidis meglumine is 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid mono (1-deoxy-1-methylamino-D-glucitol). The molecular formula is C 14 H 7 Cl 2 NO 3 C 7 H 17 NO 5 , and the molecular weight is 503.33 g/mol.

Brands: Vyndaqel, Vyndamax

Dosage form: POWDER. Active ingredients: TAFAMIDIS (35 kg/35kg). Category: BULK INGREDIENT.

Dosage form: POWDER. Active ingredients: TAFAMIDIS (1 kg/kg). Category: BULK INGREDIENT.

11. DESCRIPTION VYNDAQEL (tafamidis meglumine) and VYNDAMAX (tafamidis) contain tafamidis as the active moiety, which is a selective stabilizer of transthyretin. The chemical name of tafamidis meglumine is 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid mono (1-deoxy-1-methylamino-D-glucitol). The molecular formula is C 14 H 7 Cl 2 NO 3 C 7 H 17 NO 5 , and the molecular weight is 503.33 g/mol.

Brands: Vyndaqel, Vyndamax

Dosage form: POWDER. Active ingredients: TAFASITAMAB (200 mg/200mg). Category: DRUG FOR FURTHER PROCESSING.

11 DESCRIPTION Tafasitamab-cxix is a humanized CD19-directed cytolytic monoclonal antibody that contains an IgG1/2 hybrid Fc-domain with 2 amino acid substitutions to modify the Fc-mediated functions of the antibody. It is produced by recombinant DNA technology in mammalian cells (Chinese hamster ovary). Tafasitamab-cxix has a molecular weight of approximately 150 kDa.

Brands: Monjuvi

Malaria prophylaxis, consistent with the approved use of ARAKODA

Brands: Kodatef

11 DESCRIPTION KRINTAFEL contains tafenoquine succinate, an antimalarial agent for oral administration. The chemical name of tafenoquine succinate is (±) 8-[(4-amino-1-methylbutyl)amino]-2,6-dimethoxy-4‑methyl-5-[3-(trifluoromethyl)phenoxy]quinoline succinate. The molecular formula of tafenoquine succinate is C 24 H 28 F 3 N 3 O 3 •C 4 H 6 O 4 , and its molecular mass is 581.6 as the succinate salt (463.5 as free base). The structural formula is shown below.

Brands: Krintafel

11 DESCRIPTION ZIOPTAN (tafluprost ophthalmic solution) 0.0015% contains tafluprost, a fluorinated analog of prostaglandin F2α, for topical ophthalmic use. The chemical name for tafluprost is 1-methylethyl (5Z)-7-{(1R,2R,3R,5S)-2-[(1E)-3,3-difluoro-4-phenoxy-1-butenyl}-3,5-dihydroxycyclopentyl]-5-heptenoate. The molecular formula of tafluprost is C25H34F2O5 and its molecular weight is 452.53.

Brands: Zioptan

Dosage form: SOLUTION/ DROPS. Route: OPHTHALMIC. Active ingredients: TAFLUPROST (.0045 mg/.3mL). Category: ANDA.

Brands: Tafluprost

To remove warts such as plantar wart, flat wart, common wart and corns, calluses.

Brands: Tag Wart Remover

11 DESCRIPTION Tagraxofusp-erzs, a CD123-directed cytotoxin, is a fusion protein comprised of a recombinant human interleukin-3 (IL-3) and truncated diphtheria toxin (DT). Tagraxofusp-erzs has an approximate molecular weight of 57,695 Daltons. Tagraxofusp-erzs is constructed by recombinant DNA technology and produced in Escherichia coli cells.

Brands: Elzonris

Dosage form: POWDER. Active ingredients: SIBOFIMLOC (1 kg/kg). Category: BULK INGREDIENT.

11 DESCRIPTION Talazoparib is an inhibitor of mammalian polyadenosine 5'-diphosphoribose (ADP-ribose) polymerase (PARP) enzymes. The chemical name of talazoparib tosylate is (8 S ,9 R )-5-Fluoro-8-(4-fluorophenyl)-9-(1-methyl-1 H -1,2,4-triazol-5-yl)-2,7,8,9-tetrahydro-3 H -pyrido[4,3,2- de ]phthalazin-3-one 4-methylbenzenesulfonate (1:1). The chemical formula of talazoparib tosylate is C 26 H 22 F 2 N 6 O 4 S, and the relative molecular mass is 552.56 Daltons.

Brands: Talzenna

Dosage form: CAPSULE. Active ingredients: TALAZOPARIB TOSYLATE (.1 min/1). Category: DRUG FOR FURTHER PROCESSING.

Manufactured by SANOFI AVENTIS US. Dosage form: TABLET. Route: ORAL. Active ingredients: TALBUTAL (120MG). Application: NDA009410.

11. DESCRIPTION STERITALC (talc) is a sclerosing agent for intrapleural administration. The molecular formula for talc is Mg3Si4O10(OH)2. The molecular weight is 379.3 g/mole. The chemical name of talc is hydrated magnesium silicate. The talc powder contains ≥ 95% of hydrated magnesium silicate; associated minerals include chlorites (hydrated aluminum and magnesium silicates), magnesite (magnesium carbonate), calcite (calcium carbonate), and dolomite (calcium and magnesium carbonate).

Brands: Steritalc 2g, Steritalc 3g, Steritalc 4g

11 DESCRIPTION IBTROZI (taletrectinib) capsules contain taletrectinib adipate, a kinase inhibitor for oral use. The molecular formula for taletrectinib adipate is C 23 H 24 FN 5 O•C 6 H 10 O 4 and the molecular weight is 551.61 g/mol. The chemical name is 3-{4-[(2 R )-2-aminopropoxy]phenyl}- N -[(1 R )-1-(3-fluorophenyl)ethyl]imidazo [1,2- b ]pyridazin-6-amine monoadipate.

Brands: Ibtrozi