Drug & Medication Database

INDICATIONS: For temporary relief of needing to take control; born leaders.

Brands: Bio Vine

Brands: Vixa Skineal

11 DESCRIPTION LUPKYNIS (voclosporin) capsules, a calcineurin-inhibitor immunosuppressant, is available for administration as soft gelatin capsules containing 7.9 mg voclosporin per capsule. Inactive ingredients include alcohol, Vitamin E polyethylene glycol succinate (NF), polysorbate 40 (NF), medium-chain triglycerides (NF), gelatin, sorbitol, glycerin, iron oxide yellow, iron oxide red, titanium dioxide, and water. Voclosporin (90 to 95% trans -isomer) is the active ingredient in LUPKYNIS.

Brands: Lupkynis

Dosage form: KIT. Category: BLA.

Brands: Vonvendi

Dosage form: POWDER, FOR SOLUTION. Route: INTRAVENOUS. Active ingredients: ANTIHEMOPHILIC FACTOR HUMAN (100 [iU]/mL); VON WILLEBRAND FACTOR HUMAN (100 [iU]/mL). Category: BLA.

Brands: Wilate - Von Willebrand Factor/coagulation Factor Viii Complex (human)

11 DESCRIPTION Vonoprazan (as the fumarate), is a potassium-competitive acid blocker. Chemically, it is 1 H -pyrrole-3-methanamine, 5-(2-fluorophenyl)- N -methyl-1-(3-pyridinylsulfonyl)-, (2 E) -2-butenedioate (1:1). Its empirical formula is C 17 H 16 FN 3 O 2 S•C 4 H 4 O 4 with a molecular weight of 461.5. Vonoprazan fumarate has the following structure: Vonoprazan fumarate is white to nearly white crystals or crystalline powder, which melts at 194.8°C.

Brands: Voquezna

11 DESCRIPTION VOQUEZNA TRIPLE PAK contains vonoprazan tablets, 20 mg, amoxicillin capsules, 500 mg, and clarithromycin tablets, 500 mg for oral administration. VOQUEZNA DUAL PAK contains vonoprazan tablets, 20 mg and amoxicillin capsules, 500 mg for oral administration. Vonoprazan Tablets Vonoprazan (as the fumarate), is a potassium-competitive acid blocker (PCAB). Chemically, it is 1 H -pyrrole-3-methanamine, 5-(2-fluorophenyl)- N -methyl-1-(3-pyridinylsulfonyl)-, (2 E )-2-butenedioate (1:1).

Brands: Voquezna Dual Pak, Voquezna Triple Pak

11 DESCRIPTION VOQUEZNA TRIPLE PAK contains vonoprazan tablets, 20 mg, amoxicillin capsules, 500 mg, and clarithromycin tablets, 500 mg for oral administration. VOQUEZNA DUAL PAK contains vonoprazan tablets, 20 mg and amoxicillin capsules, 500 mg for oral administration. Vonoprazan Tablets Vonoprazan (as the fumarate), is a potassium-competitive acid blocker (PCAB). Chemically, it is 1 H -pyrrole-3-methanamine, 5-(2-fluorophenyl)- N -methyl-1-(3-pyridinylsulfonyl)-, (2 E )-2-butenedioate (1:1).

Brands: Voquezna Dual Pak, Voquezna Triple Pak

Manufactured by KEY THERAP. Dosage form: TABLET. Route: ORAL. Active ingredients: VORAPAXAR SULFATE (EQ 2.08MG BASE). Application: NDA204886.

11 DESCRIPTION VORANIGO tablets contain vorasidenib, an isocitrate dehydrogenase-1 (IDH1) and isocitrate dehydrogenase-2 (IDH2) inhibitor. Vorasidenib is present as the hemicitric acid hemihydrate co-crystal. The chemical name of the co-crystal is 6-(6-chloropyridin-2-yl)- N 2 , N 4 -bis[(2 R )-1,1,1-trifluoropropan-2-yl]-1,3,5-triazine-2,4-diamine, 2-hydroxypropane-1,2,3-tricarboxylic acid, hydrate (2:1:1).

Brands: Voranigo

11 DESCRIPTION LUXTURNA (voretigene neparvovec-rzyl) is a suspension of an adeno-associated virus vector-based gene therapy for subretinal injection. LUXTURNA is a live, non-replicating adeno-associated virus serotype 2 which has been genetically modified to express the human RPE65 gene. LUXTURNA is derived from naturally occurring adeno-associated virus using recombinant DNA techniques.

Brands: Luxturna

11 DESCRIPTION VFEND (voriconazole), an azole antifungal agent is available as a lyophilized powder for solution for intravenous infusion. The structural formula is: Voriconazole is designated chemically as (2R,3S)-2-(2, 4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1 H -1,2,4-triazol-1-yl)-2-butanol with an empirical formula of C 16 H 14 F 3 N 5 O and a molecular weight of 349.3. Voriconazole drug substance is a white to light-colored powder. VFEND I.V.

Brands: Vfend

11 DESCRIPTION ZOLINZA contains vorinostat, which is described chemically as N- hydroxy- N'- phenyloctanediamide. The empirical formula is C 14 H 20 N 2 O 3 . The molecular weight is 264.32 and the structural formula is: Vorinostat is a white to light orange powder. It is very slightly soluble in water, slightly soluble in ethanol, isopropanol and acetone, freely soluble in dimethyl sulfoxide and insoluble in methylene chloride. It has no chiral centers and is non-hygroscopic.

Brands: Zolinza

Dosage form: POWDER. Active ingredients: VORINOSTAT (55 kg/55kg). Category: BULK INGREDIENT.

Dosage form: POWDER. Active ingredients: VORINOSTAT (55 kg/55kg). Category: BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING.

11 DESCRIPTION TRINTELLIX is an immediate-release tablet for oral administration that contains the beta (β) polymorph of vortioxetine hydrobromide (HBr), an antidepressant. Vortioxetine HBr is known chemically as 1-[2-(2,4-Dimethyl-phenylsulfanyl)-phenyl]-piperazine, hydrobromide. The empirical formula is C 18 H 22 N 2 S, HBr with a molecular weight of 379.36 g/mol. The structural formula is: Vortioxetine HBr is a white to very slightly beige powder that is slightly soluble in water.

Brands: Trintellix

Dosage form: POWDER. Active ingredients: VORTIOXETINE HYDROBROMIDE (1 kg/kg). Category: BULK INGREDIENT.

Dosage form: POWDER. Active ingredients: VORTIOXETINE HYDROCHLORIDE (5 kg/5kg). Category: BULK INGREDIENT.

11 DESCRIPTION VOXZOGO contains vosoritide, a human C type natriuretic peptide (CNP) analog. Vosoritide is a 39 amino acid peptide. Its amino acid sequence includes the 37 C terminal amino acids of the human CNP53 sequence plus Pro Gly on the N terminus to convey resistance to neutral endopeptidase (NEP) degradation. Vosoritide is manufactured from Escherichia coli using recombinant DNA technology.

Brands: Voxzogo 0.4mg, Voxzogo 0.56mg, Voxzogo 1.2mg

11 DESCRIPTION OXBRYTA contains voxelotor, a hemoglobin S polymerization inhibitor. The chemical name of voxelotor is 2-hydroxy-6-((2-(1-isopropyl-1 H -pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde with a molecular formula of C 19 H 19 N 3 O 3 and a molecular weight of 337.4. The chemical structure of voxelotor is: Voxelotor is a white-to-yellow-to-beige compound in crystalline Form II of its free base.

Brands: Oxbryta

Dosage form: POWDER. Active ingredients: VOXELOTOR (1 kg/kg). Category: BULK INGREDIENT.

Dosage form: POWDER. Active ingredients: VOXELOTOR (1 kg/kg). Category: BULK INGREDIENT.

Dosage form: POWDER. Active ingredients: VOXILAPREVIR (20 kg/20kg). Category: BULK INGREDIENT.

11 DESCRIPTION AMVUTTRA contains vutrisiran, a chemically modified double-stranded small interfering ribonucleic acid (siRNA) that targets mutant and wild-type transthyretin (TTR) messenger RNA (mRNA) and is covalently linked to a ligand containing three N -acetylgalactosamine (GalNAc) residues to enable delivery of the siRNA to hepatocytes. The structural formula of vutrisiran sodium is presented below.

Brands: Amvuttra

Dosage form: POWDER. Active ingredients: VUTRISIRAN (1 g/g). Category: BULK INGREDIENT.

Dosage form: POWDER. Active ingredients: VANZACAFTOR CALCIUM (1 kg/kg). Category: BULK INGREDIENT.

Dosage form: POWDER. Active ingredients: ELEXACAFTOR (1 kg/kg). Category: BULK INGREDIENT.

Dosage form: POWDER. Active ingredients: DEUTIVACAFTOR (1 kg/kg). Category: BULK INGREDIENT.

Dosage form: POWDER. Active ingredients: TEZACAFTOR (1 kg/kg). Category: BULK INGREDIENT.

Dosage form: POWDER. Active ingredients: LUMACAFTOR (1 kg/kg). Category: BULK INGREDIENT.