Drug & Medication Database

DESCRIPTION Sterile cefotaxime sodium is a semisynthetic, broad spectrum cephalosporin antibiotic for parenteral administration. It is the sodium salt of 7-[2-(2-amino-4-thiazolyl) glyoxylamido]-3(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo [4.2.0] oct-2-ene-2-carboxylate 72 (Z)-(o-methyloxime), acetate (ester). Cefotaxime for Injection, USP contains approximately 50.5 mg (2.2 mEq) of sodium per gram of cefotaxime activity.

Brands: Cefotaxime

Brands: Cefotaxime

Dosage form: POWDER. Active ingredients: CEFOTAXIME SODIUM (1 kg/kg). Category: BULK INGREDIENT.

DESCRIPTION Cefotetan for Injection, USP, as cefotetan disodium, is a sterile, semisynthetic, broad-spectrum, beta-lactamase resistant, cephalosporin (cephamycin) antibiotic for parenteral administration. It is the disodium salt of [6R-(6α,7α)]-7-[[[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid.

Brands: Cefotetan

DESCRIPTION: Cefotetan for Injection, USP, as cefotetan disodium, is a sterile, semisynthetic, broad-spectrum, beta-lactamase resistant, cephalosporin (cephamycin) antibacterial for parenteral administration. It is the disodium salt of [6 R -(6α,7α)]-7-[[[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl]amino]-7-methoxy-3-[[(1-methyl-1 H -tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid.

Brands: Cefotetan

Manufactured by TAKEDA. Dosage form: INJECTABLE. Route: INJECTION. Active ingredients: CEFOTIAM HYDROCHLORIDE (EQ 1GM BASE/VIAL). Application: NDA050601.

Dosage form: POWDER. Active ingredients: CEFOVECIN SODIUM (1 kg/kg). Category: BULK INGREDIENT.

DESCRIPTION Cefoxitin for Injection, USP contains cefoxitin sodium a semi-synthetic, broad-spectrum cephalosporin antibiotic for parenteral administration. It is derived from cephalosporin C, which is produced by Cephalosporium Acremonium . It is the sodium salt of 3-(hydroxymethyl)-7-methoxy-8-oxo-7-[2-(2-thienyl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate carbamate (ester).

Brands: Cefoxitin

DESCRIPTION: CEFOXITIN FOR INJECTION, USP contains cefoxitin sodium a semi-synthetic, broad-spectrum cephalosporin antibiotic for parenteral administration. It is derived from cephalosporin C, which is produced by Cephalosporium Acremonium. It is the sodium salt of 3-(hydroxymethyl)-7-methoxy-8-oxo-7-[2-(2-thienyl)acetamido]-5-thia-1-azabicyclo [4.2.0] oct-2-ene-2-carboxylate carbamate (ester).

Brands: Cefoxitin

Manufactured by WYETH AYERST. Dosage form: INJECTABLE. Route: INJECTION. Active ingredients: CEFPIRAMIDE SODIUM (EQ 2GM BASE/VIAL). Application: NDA050633.

DESCRIPTION Cefpodoxime proxetil is an orally administered, extended spectrum, semi-synthetic antibiotic of the cephalosporin class. The chemical name is (RS)-1(isopropoxycarbonyloxy) ethyl (+)-(6R,7R)-7-[2-(2-amino-4-thiazolyl)-2-{(Z)methoxyimino}acetamido]-3-methoxymethyl-8-oxo-5-thia-1-azabicyclo [4.2.0]oct-2-ene- 2-carboxylate. Its molecular formula is C 21 H 27 N 5 O 9 S 2 and its structural formula is represented below: The molecular weight of cefpodoxime proxetil is 557.6.

Brands: Cefpodoxime Proxetil

Dosage form: POWDER. Active ingredients: CEFPODOXIME PROXETIL (50 kg/50kg). Category: BULK INGREDIENT.

DESCRIPTION Cefprozil is a semi-synthetic broad-spectrum cephalosporin antibiotic. Cefprozil is a cis and trans isomeric mixture (≥90% cis). The chemical name for the monohydrate is (6 R ,7 R )-7-[( R )-2-Amino-2-( p -hydroxyphenyl)acetamido]-8-oxo-3-propenyl-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2- carboxylic acid monohydrate, and the structural formula is: Cefprozil is a white to yellowish powder with a molecular formula for the monohydrate of C 18 H 19 N 3 O 5 S.H 2 O and a molecular weight of.

Brands: Cefprozil

11. DESCRIPTION Ceftaroline fosamil for injection is a sterile, semi-synthetic, prodrug of the cephalosporin antibacterial class of beta-lactams (β- lactams). Chemically, the prodrug, ceftaroline fosamil monoacetate is (6 R ,7 R )-7-{(2 Z )-2-(ethoxyimino)-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetamido}-3-{[4-(1-methylpyridin-1-ium-4- yl)-1,3-thiazol-2-yl]sulfanyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate monoacetate. Its molecular weight is 744.74.

Brands: Ceftaroline Fosamil

DESCRIPTION Ceftazidime is a semisynthetic, broad-spectrum, beta-lactam antibacterial drug for parenteral administration. It is the pentahydrate of pyridinium, 1-[[7-[[(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy) imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, hydroxide, inner salt, [6R-[6α,7β(Z)]]. It has the following structure: The molecular formula is C 22 H 32 N 6 O 12 S 2 , representing a molecular weight of 636.6.

Brands: Tazicef

Manufactured by PAI HOLDINGS PHARM. Dosage form: INJECTABLE. Route: INJECTION. Active ingredients: CEFTAZIDIME SODIUM (EQ 20MG BASE/ML). Application: NDA050634.

11 DESCRIPTION AVYCAZ is an antibacterial combination product consisting of the semisynthetic cephalosporin ceftazidime pentahydrate and the beta-lactamase inhibitor avibactam sodium for intravenous administration. Ceftazidime Ceftazidime is a semisynthetic, beta-lactam antibacterial drug. It is the pentahydrate of (6 R ,7 R , Z )-7-(2-(2-aminothiazol-4-yl)-2-(2-carboxypropan-2-yloxyimino)acetamido)-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate.

Brands: Avycaz

Dosage form: POWDER. Active ingredients: AVIBACTAM SODIUM (.2 kg/kg); CEFTAZIDIME (.8 kg/kg). Category: DRUG FOR FURTHER PROCESSING.

Manufactured by BURKE THERAP. Dosage form: CAPSULE. Route: ORAL. Active ingredients: CEFTIBUTEN DIHYDRATE (EQ 400MG BASE). Application: NDA050685.

Dosage form: POWDER. Active ingredients: CEFTIOFUR (1 kg/kg). Category: BULK INGREDIENT.

Dosage form: POWDER. Active ingredients: CEFTIOFUR (1 kg/kg). Category: BULK INGREDIENT.

Dosage form: POWDER. Active ingredients: CEFTIOFUR HYDROCHLORIDE (1 kg/kg). Category: BULK INGREDIENT.

Dosage form: POWDER. Active ingredients: CEFTIOFUR SODIUM (1 kg/kg). Category: BULK INGREDIENT.

Manufactured by ASTELLAS. Dosage form: INJECTABLE. Route: INJECTION. Active ingredients: CEFTIZOXIME SODIUM (EQ 1GM BASE/VIAL). Application: NDA050560.

11 DESCRIPTION ZEVTERA (ceftobiprole medocaril sodium for injection) contains sodium salt of ceftobiprole medocaril, a semisynthetic, cephalosporin antibacterial, for intravenous use. Chemically, ceftobiprole medocaril is (6 R ,7 R )-7-[[(2 Z )-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-hydroxyiminoacetyl]amino]-3-[( E )-[1-[(3 R )-1-[(5-methyl-2-oxo-1,3-dioxol-4-yl)methoxycarbonyl]pyrrolidin-3-yl]-2-oxopyrrolidin-3-ylidene]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid.

Brands: Zevtera

Dosage form: INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION. Active ingredients: CEFTOBIPROLE MEDOCARIL SODIUM (500 mg/mL). Category: DRUG FOR FURTHER PROCESSING.

11 DESCRIPTION ZERBAXA (ceftolozane and tazobactam) is an antibacterial combination product consisting of the cephalosporin antibacterial drug ceftolozane sulfate and the beta-lactamase inhibitor tazobactam sodium for intravenous administration. Ceftolozane sulfate is a semi-synthetic antibacterial drug of the beta-lactam class for parenteral administration.

Brands: Zerbaxa

Dosage form: POWDER. Active ingredients: CEFTOLOZANE SULFATE (1 kg/kg). Category: BULK INGREDIENT.

DESCRIPTION Ceftriaxone for Injection, USP is a sterile, semisynthetic, broad-spectrum cephalosporin antibiotic for intravenous or intramuscular administration. Ceftriaxone sodium is (6 R ,7 R )-7-[2-(2-Amino-4-thiazolyl)glyoxylamido]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo- as -triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7 2 -( Z )-( O -methyloxime), disodium salt, sesquaterhydrate.

Brands: Ceftriaxone

Ceftriaxone sodium is a prescription broad-spectrum cephalosporin antibiotic given by injection for serious bacterial infections including meningitis, pneumonia, and septicemia.

Brands: Ceftriaxone Sodium